SynthesisCognitive behaviour therapy2017
Effect of treatments for depression on quality of life: a meta-analysis.
Synthesis in Cognitive behaviour therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Effectiveness of unguided web-based interventions for the treatment of depressive symptoms in improving the quality of life: a meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Pooled it
- The Efficacy of Individual Cognitive Behavioral Therapy for Eating Disorders: A Meta-Analysis of Randomized Controlled Trials.The International journal of eating disorders · 2025Pooled it
- The biological relationship among depression, vitamins BFrontiers in nutrition · 2025Pooled it
- Home-based rehabilitation versus centre-based programs in patients with temporomandibular disorders-a systematic review and meta-analysis.Journal of oral & facial pain and headache · 2024Pooled it
- Dextromethorphan-Bupropion for the Treatment of Depression: A Systematic Review of Efficacy and Safety in Clinical Trials.CNS drugs · 2023Pooled it
- Effect of antidepressants on functioning and quality of life outcomes in children and adolescents with major depressive disorder: a systematic review and meta-analysis.Translational psychiatry · 2022Pooled it
- Electroacupuncture as a rapid-onset and safer complementary therapy for depression: A systematic review and meta-analysis.Frontiers in psychiatry · 2022Pooled it
- Anxiety, Depression and Quality of Life-A Systematic Review of Evidence from Longitudinal Observational Studies.International journal of environmental research and public health · 2021Pooled it
- Quality of life in "chronic" cancer survivors: a meta-analysis.Journal of cancer survivorship : research and practice · 2020Pooled it
- Evaluation of the internet-based intervention "Selfapy" in participants with unipolar depression and the impact on quality of life: a randomized, parallel group study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Trial
- Cognitive-behavioral group therapy in major depressive disorder with focus on self-esteem and optimism: an interventional study.BMC psychiatry · 2022Trial
- Increased global integration in the brain after psilocybin therapy for depression.Nature medicine · 2022Trial
- Efficacy of cognitive behavioural therapy in medicated adults with attention-deficit/hyperactivity disorder in multiple dimensions: a randomised controlled trial.European archives of psychiatry and clinical neuroscience · 2022Trial
- Using Machine Learning to Analyze the Predictors of Life Satisfaction: Focus on Lifestyle Attitudes and Psychological Factors.International journal of methods in psychiatric research · 2026Article
- Identifying Evidence-Based Strategies in a Digital Mental Health Intervention for Depression: Qualitative Content Analysis.Journal of medical Internet research · 2026Article
- From cigarettes to symptoms: the association between smoking and depression in the German National Cohort (NAKO).BMC public health · 2025Article
- The nature of the relation between mental well-being and ill-being.Nature human behaviour · 2025Review
- The effects of rTMS on self-reported quality of life in younger and older adults with major depressive disorder.Psychological medicine · 2025Article
- The Potential of Transcranial Direct Current Stimulation (tDCS) in Improving Quality of Life in Patients with Multiple Sclerosis: A Review and Discussion of Mechanisms of Action.Journal of clinical medicine · 2025Review
- Maternal depressive symptoms trajectories and harsh parenting: the mediating role of maternal quality of life in the 2004 Pelotas Birth Cohort.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Cognitive-behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) are the two first-line treatments for depression, but little is known about their effects on quality of life (QOL). A meta-analysis was conducted to examine changes in QOL in adults with major depressive disorder who received CBT (24 studies examining 1969 patients) or SSRI treatment (13 studies examining 4286 patients) for their depression. Moderate improvements in QOL from pre to post-treatment were observed in both CBT (Hedges' g = .63) and SSRI (Hedges' g = .79) treatments. The effect size remained stable over the course of the follow-up period for CBT. No data were available to examine follow-ups in the SSRI group. QOL effect sizes decreased linearly with publication year, and greater improvements in depression were significantly associated with greater improvements in QOL for CBT, but not for SSRIs. CBT and SSRIs for depression were both associated with moderate improvements in QOL, but are possibly caused by different mechanisms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.