Observational studyJournal of veterinary internal medicine2017
Comparison of Preoperative Quantitative Magnetic Resonance Imaging and Clinical Assessment of Deep Pain Perception as Prognostic Tools for Early Recovery of Motor Function in Paraplegic Dogs with Intervertebral Disk Herniations.
Observational study in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Computed tomography versus magnetic resonance imaging for the perioperative management of acute thoracolumbar intervertebral disc extrusion in non-ambulatory chondrodystrophic dogs.Veterinary surgery : VS · 2026Article
- Comparative cost-effectiveness of cross-sectional imaging strategies in the diagnosis of intervertebral disc extrusion in dogs: a United Kingdom-based decision-analytic study.Journal of veterinary internal medicine · 2026Article
- Diagnostic and Prognostic Value of Serum Neurofilament Light Chain in Canine Spinal Cord Diseases.Veterinary sciences · 2025Article
- Machine learning and quantitative computed tomography radiomics prediction of postoperative functional recovery in paraplegic dogs.Veterinary surgery : VS · 2025Article
- Machine-learning-based prediction of functional recovery in deep-pain-negative dogs after decompressive thoracolumbar hemilaminectomy for acute intervertebral disc extrusion.Veterinary surgery : VS · 2025Article
- Outcomes of non-limited versus cranial-limited extensive hemilaminectomy and durotomy in dogs with thoracolumbar intervertebral disc extrusion and presumptive progressive myelomalacia.BMC veterinary research · 2025Article
- Physiotherapy in the Recovery of Paraplegic Dogs without Nociception Due to Thoracolumbar Intervertebral Disc Extrusion Treated Surgically.Animals : an open access journal from MDPI · 2024Article
- Outcome in paraplegic dogs with or without pain perception due to thoracolumbar fibrocartilaginous embolic myelopathy or acute non-compressive nucleus pulposus extrusion.Frontiers in veterinary science · 2024Article
- A case series of 37 surgically managed, paraplegic, deep pain negative French bulldogs, with thoracolumbar intervertebral disc extrusion, from two English referral centres.Veterinary record open · 2023Article
- Diagnostic and Treatment of Spinal Fracture and Luxation in Italian Wolves (Animals : an open access journal from MDPI · 2022Article
- ACVIM consensus statement on diagnosis and management of acute canine thoracolumbar intervertebral disc extrusion.Journal of veterinary internal medicine · 2022Article
- Association of hydromyelia and acute compressive myelopathy caused by intervertebral disc extrusion in dogs.Journal of veterinary internal medicine · 2022Article
- Spinal Cord Signal Change on Magnetic Resonance Imaging May Predict Worse Clinical In- and Outpatient Outcomes in Patients with Spinal Cord Injury: A Prospective Multicenter Study in 459 Patients.Journal of clinical medicine · 2021Article
- Evaluation of the involvement of Th17-cells in the pathogenesis of canine spinal cord injury.PloS one · 2021Article
- Magnetization transfer and diffusion tensor imaging in dogs with intervertebral disk herniation.Journal of veterinary internal medicine · 2020Article
- Prognostic Factors in Canine Acute Intervertebral Disc Disease.Frontiers in veterinary science · 2020Review
- Diagnostic Imaging in Intervertebral Disc Disease.Frontiers in veterinary science · 2020Review
- Ambulation in Dogs With Absent Pain Perception After Acute Thoracolumbar Spinal Cord Injury.Frontiers in veterinary science · 2020Review
- The role of diffusion tensor imaging as an objective tool for the assessment of motor function recovery after paraplegia in a naturally-occurring large animal model of spinal cord injury.Journal of translational medicine · 2018Article
- Transcranial magnetic motor evoked potentials and magnetic resonance imaging findings in paraplegic dogs with recovery of motor function.Journal of veterinary internal medicine · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrognostic tools to predict early postoperative motor function recovery (MFR) after thoracolumbar intervertebral disk herniation (IVDH) in paraplegic dogs represent an opportunity to timely implement novel therapies that could shorten recovery times and diminish permanent neurological dysfunctions. HYPOTHESIS: Fractional anisotropy (FA) values obtained using diffusion tensor imaging have a higher prognostic value than a lesion extension ratio in T2-weighted images (T2W-LER) and clinical assessment of deep pain perception (DPP) for MFR. ANIMALS: Thirty-five paraplegic dogs with diagnosis of acute or subacute thoracolumbar IVDH.
methodsProspective, descriptive observational study. At admission, absence or presence of DPP, T2W-LER, and FA values was evaluated. MFR was assessed within 4 weeks after decompressive surgery. Values of T2W-LER and FA of dogs with and without MFR were compared using t-tests. All 3 methods were evaluated for their sensitivity and specificity as a prognostic factor.
resultsNo differences were found between groups regarding T2W-LER. FA values differed statistically when measured caudally of lesion epicenter being higher in dogs without MFR compared to dogs with MFR (P = .023). Logistic regression analysis revealed significance in FA values measured caudally of the lesion epicenter (P = .033, area under the curve = 0.72). Using a cutoff value of FA = 0.660, the technique had a sensitivity of 80% and a specificity of 55%. Evaluation of DPP had a sensitivity of 73.3% and specificity of 75% (P = .007). CONCLUSIONS AND CLINICAL IMPORTANCE: Evaluation of DPP showed a similar sensitivity and a better specificity predicting early MFR than quantitative magnetic resonance imaging.
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