Questioning antiviral RNAi in mammals.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

22 citing papers in PubMed.

1. Nuclear AGO2 supports influenza A virus replication through type-I interferon regulation.Nucleic acids research · 2025
   Article
2. Ancestral protein reconstruction reveals evolutionary events governing variation in Dicer helicase function.eLife · 2023
   Article
3. Dicer and PKR as Novel Regulators of Embryonic Stem Cell Fate and Antiviral Innate Immunity.Journal of immunology (Baltimore, Md. : 1950) · 2022
   Review
4. siRNA Therapeutics against Respiratory Viral Infections-What Have We Learned for Potential COVID-19 Therapies?Advanced healthcare materials · 2021
   Review
5. Breast Cancer and the Other Non-Coding RNAs.International journal of molecular sciences · 2021
   Review
6. Ebola Virus Produces Discrete Small Noncoding RNAs Independently of the Host MicroRNA Pathway Which Lack RNA Interference Activity in Bat and Human Cells.Journal of virology · 2020
   Article
7. Extracellular RNA in viral-host interactions: Thinking outside the cell.Wiley interdisciplinary reviews. RNA · 2019
   Review
8. Slicing and dicing viruses: antiviral RNA interference in mammals.The EMBO journal · 2019
   Review
9. The underdeveloped innate immunity in embryonic stem cells: The molecular basis and biological perspectives from early embryogenesis.American journal of reproductive immunology (New York, N.Y. : 1989) · 2019
   Article
10. Antiviral resistance of stem cells.Current opinion in immunology · 2019
    Review
11. Evolution of Immune Systems From Viruses and Transposable Elements.Frontiers in microbiology · 2019
    Review
12. Harnessing host-virus evolution in antiviral therapy and immunotherapy.Clinical & translational immunology · 2019
    Review
13. Unleashing the Full Potential of Oncolytic Adenoviruses against Cancer by Applying RNA Interference: The Force Awakens.Cells · 2018
    Review
14. MicroRNA-Attenuated Virus Vaccines.Non-coding RNA · 2018
    Review
15. Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes.PLoS genetics · 2018
    Article
16. The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells.The EMBO journal · 2018
    Article
17. Small RNA-Omics for Plant Virus Identification, Virome Reconstruction, and Antiviral Defense Characterization.Frontiers in microbiology · 2018
    Review
18. RNA Interference as a Prospective Tool for the Control of Human Viral Infections.Frontiers in microbiology · 2018
    Review
19. Viruses Seen by Our Cells: The Role of Viral RNA Sensors.Journal of immunology research · 2018
    Review
20. RNA Interference Therapies for an HIV-1 Functional Cure.Viruses · 2017
    Review

Corrections and comments

• Commented on by
  Reply to 'Questioning antiviral RNAi in mammals'.2017
• Comment on
  Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells.2016

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as