ArticleObesity (Silver Spring, Md.)2017
Ability to adjust nocturnal fat oxidation in response to overfeeding predicts 5-year weight gain in adults.
Article in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- The association between gut hormones and diet-induced metabolic flexibility in metabolically healthy adults.Obesity (Silver Spring, Md.) · 2023Trial
- Late-Night Overeating and All-Cause and Cardiovascular Disease Mortality in Adults Aged ≥ 50: A Cohort Study.The journal of nutrition, health & aging · 2023Article
- Metabolic profile in women differs between high versus low energy spenders during a low intensity exercise on a cycle-desk.Scientific reports · 2022Article
- Review
- Circadian Rhythm of Substrate Oxidation and Hormonal Regulators of Energy Balance.Obesity (Silver Spring, Md.) · 2020Article
- Impact of Exercise and Activity on Weight Regain and Musculoskeletal Health Post-Ovariectomy.Medicine and science in sports and exercise · 2019Article
- Metabolic Determinants of Weight Gain in Humans.Obesity (Silver Spring, Md.) · 2019Review
- Reasons for Late-Night Eating and Willingness to Change:A Qualitative Study in Pregnant Black Women.Journal of nutrition education and behavior · 2019Article
- Effect of frequent interruptions of sedentary time on nutrient metabolism in sedentary overweight male and female adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Article
- Associations Among Dietary Fat Oxidation Responses to Overfeeding and Weight Gain in Obesity-Prone and Resistant Adults.Obesity (Silver Spring, Md.) · 2018Article
- Free-Living Responses in Energy Balance to Short-Term Overfeeding in Adults Differing in Propensity for Obesity.Obesity (Silver Spring, Md.) · 2018Article
- Classical experiments in whole-body metabolism: open-circuit respirometry-diluted flow chamber, hood, or facemask systems.European journal of applied physiology · 2018Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveTo determine whether metabolic responses to short-term overfeeding predict longitudinal changes in body weight.
methodsTwenty-four-hour energy expenditure (EE) and substrate utilization were measured at baseline in a room calorimeter following 3 days of eucaloric and hypercaloric feeding (40% excess) in a sample of lean adults (n: 34; age: 28 ± 2 y; BMI: 22 ± 3 kg/m
resultsOverfeeding increased EE and reduced fat oxidation when examined over the 24-hour, waking, and nocturnal periods. Absolute change in body mass over 5 years was 3.0 ± 0.6 kg (average rate of change = 0.7 ± 0.1 kg/y, P < 0.001). Lower nocturnal (but not 24-hour or waking) fat oxidation (r = -0.42, P = 0.01) and EE (r = -0.33, P = 0.05) with overfeeding were the strongest predictors of 5-year weight gain. When adjusted for covariates, changes in nocturnal fat oxidation and EE with overfeeding predicted 41% of the variance in weight change (P = 0.02).
conclusionsFailure to maintain fat oxidation at night following a period of overfeeding appears to be associated with a metabolic phenotype favoring weight gain.
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Registered trials
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