Evidence map›Paper›PMID 28440033›Full record

ArticleAnnals of neurology2017

Rigor, reproducibility, and in vitro cerebrospinal fluid assays: The devil in the details.

Olivia A Moody, Sahil Talwar, Meagan A Jenkins, Amanda A Freeman, Lynn Marie Trotti, Paul S García, Donald Bliwise, Joseph W Lynch, Brad Cherson, Eric M Hernandez and 4 more

Abstract readLetterComment
In one paragraph

Article in Annals of neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Olivia A MoodyProgram in Neuroscience, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA.
Sahil TalwarQueensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.
Meagan A JenkinsM. Jenkins Medical Communications, Decatur, GA.
Amanda A FreemanCenter for the Study of Human Health, Emory College, Atlanta, GA.
Lynn Marie TrottiDepartment of Neurology and Emory Program in Sleep, Emory University School of Medicine, Atlanta, GA.
Paul S GarcíaProgram in Neuroscience, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA.
Donald BliwiseDepartment of Neurology and Emory Program in Sleep, Emory University School of Medicine, Atlanta, GA.
Joseph W LynchQueensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.
Brad ChersonPavilion Compounding Pharmacy, Atlanta, GA.
Eric M HernandezNoran Neurological Clinic, Minneapolis, MN.
Neil FeldmanSt Petersburg Sleep Disorders Center, St Petersburg, FL.
Prabhjyot SainiDepartment of Neurology and Emory Program in Sleep, Emory University School of Medicine, Atlanta, GA.
David B RyeProgram in Neuroscience, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA.
Andrew JenkinsProgram in Neuroscience, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA.

Funding

Graduate Training in the Pharmacological StudiesT32GM008602 · NIGMS · EMORY UNIVERSITY · PI HALL, RANDY A. · 1996 to 2021
$5.1M
TRAINING IN TRANSLATIONAL RESEARCH IN NEUROLOGYT32NS007480 · NINDS · EMORY UNIVERSITY · PI LEVEY, ALLAN I · 2000 to 2020
$4.5M
Characterization of an endogenous GABA-ergic mechanism underlying hypersomniaR01NS089719 · NINDS · EMORY UNIVERSITY · PI RYE, DAVID B · 2015 to 2018
$2.4M
Sleepiness and sleep drunkenness: narcolepsy versus GABA-related hypersomniaK23NS083748 · NINDS · EMORY UNIVERSITY · PI TROTTI, LYNN MARIE · 2014 to 2018
$918k
Effects of Antiretrovirals on Neuronal Health: Screening ARVs for NeurotoxicityIK2BX001677 · VA · VETERANS HEALTH ADMINISTRATION · PI GARCIA, PAUL S · 2014 to 2018
–
BLRD VA IK2 BX001677NIGMS NIH HHS T32 GM008602NINDS NIH HHS K23 NS083748NINDS NIH HHS R01 NS089719NINDS NIH HHS T32 NS007480
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disorders of Excessive SomnolenceReceptors, GABAgamma-Aminobutyric AcidHumansReproducibility of ResultsResearch Designgamma-Aminobutyric AcidReceptors, GABA

Identifiers

PMID28440033
PMCPMC5639705

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.