Evidence map›Paper›PMID 28439719›Full record

ReviewInsights into imaging2017

Radiological imaging of teratological fetuses: what can we learn?

Lucas L Boer, A N Schepens-Franke, J J A van Asten, D G H Bosboom, K Kamphuis-van Ulzen, T L Kozicz, D J Ruiter, R-J Oostra, W M Klein

Abstract readReview
In one paragraph

Review in Insights into imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Dutch teratological collections and their artistic portrayals.American journal of medical genetics. Part C, Seminars in medical genetics · 2021
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lucas L BoerDepartment of Anatomy and Museum for Anatomy and Pathology, Radboud University Medical Centre, Geert Grooteplein Noord 21, 6525 EZ, Nijmegen, The Netherlands. Lucas.boer@radboudumc.nl.
A N Schepens-FrankeDepartment of Anatomy and Museum for Anatomy and Pathology, Radboud University Medical Centre, Geert Grooteplein Noord 21, 6525 EZ, Nijmegen, The Netherlands.
J J A van AstenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
D G H BosboomDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
K Kamphuis-van UlzenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
T L KoziczDepartment of Anatomy and Museum for Anatomy and Pathology, Radboud University Medical Centre, Geert Grooteplein Noord 21, 6525 EZ, Nijmegen, The Netherlands.
D J RuiterDepartment of Anatomy and Museum for Anatomy and Pathology, Radboud University Medical Centre, Geert Grooteplein Noord 21, 6525 EZ, Nijmegen, The Netherlands.
R-J OostraDepartment of Anatomy, Embryology and Physiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
W M KleinDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the advantages of radiological imaging of a collection of full-term teratological fetuses in order to increase their scientific and educational value.

backgroundAnatomical museums around the world exhibit full-term teratological fetuses. Unfortunately, these museums are regularly considered as "morbid cabinets". Detailed dysmorphological information concerning the exhibited specimens is often lacking. Moreover, fetuses with severe and complex congenital anomalies are frequently diagnosed incompletely, incorrectly or not at all.

methodsIn order to verify diagnoses and to enrich their educational and scientific value, we imaged 41 out of the 72 teratological specimens present in the collection of our Anatomy and Pathology Museum in Nijmegen (The Netherlands) by means of magnetic resonance imaging (MRI) and computed tomography (CT). Additionally, contemporary dysmorphological insights and 3D models are implemented in the teratology education of medical students and residents.

conclusionsFull-term teratological fetuses have become increasingly rare and deserve a prominent place in every anatomical museum; they are suitable for contemporary teratological research and education. Modern radiological techniques markedly enhance their scientific and didactic value. TEACHING POINTS: • To explore the scientific and educational potential of institutionalised teratological collections • To understand the additional value of radiological imaging in diagnosing teratological specimens • To learn about the specific settings of MRI parameters when scanning fixed specimens • To recognise specific internal dysmorphology in several congenital anomalies.

Indexed as

Computed tomographyCongenital anomalyEducationMagnetic resonance imagingTeratology

Identifiers

PMID28439719
PMCPMC5438317

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.