ArticleEuropean radiology2017
Differences in tibial subchondral bone structure evaluated using plain radiographs between knees with and without cartilage damage or bone marrow lesions - the Oulu Knee Osteoarthritis study.
Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Bone Density and Texture from Minimally Post-Processed Knee Radiographs in Subjects with Knee Osteoarthritis.Annals of biomedical engineering · 2019Trial
- Weaker subchondral bone and thinner articular cartilage of the knee are associated with elevated baseline fracture risk independently of osteoarthritis risk factors.Archives of osteoporosis · 2025Article
- Individuals with Knee Osteoarthritis and Osteoporosis Represent a Distinctive Subgroup Whose Symptoms Originate from Differences in Subchondral Bone Rather than Cartilage.Calcified tissue international · 2024Article
- Functional scores and prosthetic implant placement are different for navigated medial UKA left in varus alignment.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Radiographic Biomarkers for Knee Osteoarthritis: A Narrative Review.Life (Basel, Switzerland) · 2023Review
- Trabecular bone texture analysis of conventional radiographs in the assessment of knee osteoarthritis: review and viewpoint.Arthritis research & therapy · 2021Review
- Principal Component Analysis of Simultaneous PET-MRI Reveals Patterns of Bone-Cartilage Interactions in Osteoarthritis.Journal of magnetic resonance imaging : JMRI · 2020Article
- Quantifying Subresolution 3D Morphology of Bone with Clinical Computed Tomography.Annals of biomedical engineering · 2020Article
- Comparison of bone texture between normal individuals and patients with Kashin-Beck disease from plain radiographs in knee.Scientific reports · 2018Article
- Association of subchondral bone texture on magnetic resonance imaging with radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative Bone Ancillary Study.European radiology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate whether subchondral bone structure from plain radiographs is different between subjects with and without articular cartilage damage or bone marrow lesions (BMLs).
methodsRadiography-based bone structure was assessed from 80 subjects with different stages of knee osteoarthritis using entropy of Laplacian-based image (E
resultsSubjects with medial tibial cartilage damage had significantly higher FD
conclusionsOur results support the use of bone structural analysis from radiographs when examining subjects with osteoarthritis or at risk of having it. KEY POINTS: • Knee osteoarthritis causes changes in articular cartilage and subchondral bone • Magnetic resonance imaging is a comprehensive imaging modality for knee osteoarthritis • Radiography-based bone structure analysis can provide additional information of osteoarthritic subjects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.