Evidence map›Paper›PMID 28439563›Full record

ArticleScience advances2017

Mechanism of Vps4 hexamer function revealed by cryo-EM.

Min Su, Emily Z Guo, Xinqiang Ding, Yan Li, Jeffrey T Tarrasch, Charles L Brooks, Zhaohui Xu, Georgios Skiniotis

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  7. Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin.bioRxiv : the preprint server for biology · 2024
    Article
  8. Visualization of the Cdc48 AAA+ ATPase protein unfolding pathway.bioRxiv : the preprint server for biology · 2023
    Article
  9. The Machinery of Exosomes: Biogenesis, Release, and Uptake.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Tools for visualizing and analyzing Fourier space sampling in Cryo-EM.Progress in biophysics and molecular biology · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Min SuLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Emily Z GuoLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-8199-0274
Xinqiang DingDepartment of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Yan LiLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Jeffrey T TarraschLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Charles L BrooksDepartment of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI 48109, USA.ORCID 0000-0002-8149-5417
Zhaohui XuLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-2085-0470
Georgios SkiniotisLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0003-0238-7846
University of Michigan · US

Funding

Theoretical Studies of Receptor-Ligand InteractionsR01GM037554 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, CHARLES L · 1987 to 2018
$3.8M
Architectural Basis of Leptin Transmembrane SignalingR01DK090165 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SKINIOTIS, GEORGIOS · 2011 to 2017
$2.3M
Structural Basis of Membrane Scission: Regulation of the Vps4 ATPase ComplexR01GM095769 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, ZHAOHUI · 2011 to 2014
$1.2M
Silicon Mechanics Compute ClusterS10OD020011 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SKINIOTIS, GEORGIOS · 2015 to 2015
$490k
NIDDK NIH HHS R01 DK090165NIGMS NIH HHS R01 GM037554NIGMS NIH HHS R01 GM095769NIH HHS S10 OD020011
6 · The paper itself

Abstract

Vps4 is a member of AAA

Indexed as

AAA+ ATPasescryoEMESCRT IIIESCRT pathwayvps4 structure

Identifiers

PMID28439563
PMCPMC5392032
OpenAlexW2607322700

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.