Evidence map›Paper›PMID 28438984›Full record

ArticlePhysiological reports2017

Comparison of multiple non-invasive methods of measuring cardiac output during pregnancy reveals marked heterogeneity in the magnitude of cardiac output change between women.

John W Petersen, Jing Liu, Yueh-Yun Chi, Melissa Lingis, R Stan Williams, Alice Rhoton-Vlasak, Mark S Segal, Kirk P Conrad

Abstract readComparative Study
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Observational
  5. Article
  6. Is a frozen embryo transfer in a programmed cycle really the best option?Journal of assisted reproduction and genetics · 2019
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John W PetersenDivision of Cardiovascular Medicine, University of Florida, Gainesville, Florida john.petersen@medicine.ufl.edu.
Jing LiuDepartment of Biostatistics, University of Florida, Gainesville, Florida.
Yueh-Yun ChiDepartment of Biostatistics, University of Florida, Gainesville, Florida.
Melissa LingisDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida, Gainesville, Florida.
R Stan WilliamsDepartment of Obstetrics and Gynecology, University of Florida, Gainesville, Florida.
Alice Rhoton-VlasakDepartment of Obstetrics and Gynecology, University of Florida, Gainesville, Florida.
Mark S SegalDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida, Gainesville, Florida.
Kirk P ConradDepartment of Obstetrics and Gynecology, University of Florida, Gainesville, Florida.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
NCATS NIH HHS UL1 TR001427
6 · The paper itself

Abstract

Various non-invasive methods are available to measure cardiac output (CO) during pregnancy. We compared serial measures of CO using various methods to determine which provided the least variability. Ten patients with spontaneous pregnancy had estimation of CO at baseline prior to becoming pregnant and at the end of the first and third trimesters. Echocardiographic data were used to estimate CO using the Teichholz method, Simpson's biplane method, and the Doppler determined velocity time integral (VTI) method. In addition, a Bioz Dx device was used to estimate CO by impedance cardiography. CO estimated with the VTI method had the lowest beat-to-beat variability. CO estimated with the VTI method was higher than CO estimated with the 2D-Teichholz method and Simpson's method. The percent change in CO during pregnancy was similar for all echo methods (VTI, Teichholz, and Simpson's biplane). Baseline CO determined with impedance cardiography was higher than CO determined with the VTI method. However, change in CO during pregnancy was significantly lower when measured with impedance cardiography. There was marked heterogeneity in the degree of rise in CO during the first trimester (-3 to 55%). The wide variation in the gestational rise in CO was unexpected, and at least in part secondary to variable increase in heart rate. We recommend the use of the Doppler determined VTI method for the estimation of CO in pregnancy.

Indexed as

Cardiac OutputAdultAnalysis of VarianceEchocardiographyFemaleHumansPregnancyCardiac Outputechocardiographypregnancy

Identifiers

PMID28438984
PMCPMC5408281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.