Evidence map›Paper›PMID 28438938›Full record

ArticleAntimicrobial agents and chemotherapy2017

A Tick Antivirulence Protein Potentiates Antibiotics against Staphylococcus aureus.

Nabil M Abraham, Lei Liu, Brandon L Jutras, Kristen Murfin, Ali Acar, Timur O Yarovinsky, Erica Sutton, Martin Heisig, Christine Jacobs-Wagner, Erol Fikrig

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Nabil M AbrahamSection of Infectious Disease, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Lei LiuSection of Infectious Disease, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Brandon L JutrasHoward Hughes Medical Institute, Chevy Chase, Maryland, USA.
Kristen MurfinSection of Infectious Disease, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Ali AcarSection of Infectious Disease, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Timur O YarovinskySection of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Erica SuttonSection of Infectious Disease, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Martin HeisigSection of Infectious Disease, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Christine Jacobs-WagnerHoward Hughes Medical Institute, Chevy Chase, Maryland, USA.
Erol FikrigSection of Infectious Disease, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA erol.fikrig@yale.edu.
Yale University · USHoward Hughes Medical Institute · USNaval Academy · TR

Funding

IMMUNOHEMATOLOGY/TRANSFUSION MEDICINE RESEARCH TRAININGT32HL007974 · NHLBI · YALE UNIVERSITY · PI JEANNE E HENDRICKSON, Diane S Krause · 2001 to 2026
$8.1M
The role of tick gut microbiota in Borrelia burgdorferi transmission to miceR01AI126033 · NIAID · YALE UNIVERSITY · PI FIKRIG, EROL, NARASIMHAN, SUKANYA · 2017 to 2020
$1.7M
Howard Hughes Medical InstituteNHLBI NIH HHS T32 HL007974NIAID NIH HHS R01 AI126033
6 · The paper itself

Abstract

New strategies are needed to combat antibiotic resistance, especially against pathogens such as methicillin-resistant

Indexed as

AnimalsAnti-Bacterial AgentsAntifreeze ProteinsBiofilmsMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsStaphylococcus aureusTicksAnti-Bacterial AgentsAntifreeze Proteinsantibioticsantifreeze proteinbiofilmsStaphylococcus aureus

Identifiers

PMID28438938
PMCPMC5487661
OpenAlexW2608866761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.