ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2017
Lyme disease ecology in a changing world: consensus, uncertainty and critical gaps for improving control.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
135 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global seroprevalence and sociodemographic characteristics ofBMJ global health · 2022Pooled it
- High-resolution prediction and risk mapping ofiScience · 2026Article
- 'Reservoir dogs': The emerging zoonotic risk associated with European dog imports to the UK.The Veterinary record · 2026Review
- Mapping tick-borne hazard across gradients of urban intensity in metropolitan regions.Parasites & vectors · 2026Article
- Global risk assessment of Lyme borreliosis transmission.Pathogens and global health · 2026Article
- Scientist's Opinion on Climate Change and Hard Ticks (Ixodidae).Pathogens (Basel, Switzerland) · 2026Article
- Variation in pathogen load and the pathogen load-infectiousness relationship broaden avian malaria's distribution.Nature communications · 2026Article
- Environmental hazard of tick-borne diseases in urban and peri-urban sites in an endemic area of eastern France.Parasite (Paris, France) · 2026Article
- Prevalence ofPathogens (Basel, Switzerland) · 2025Article
- Genetic landscape of Borrelia burgdorferi sensu stricto in Canada: a study of genetic diversity.Scientific reports · 2025Article
- Beyond Species Richness: The Importance of Phylogenetic Dimensions of Biodiversity in Disease Ecology.Integrative and comparative biology · 2025Review
- An atlas for tick immune cells.Nature microbiology · 2025Article
- Evaluation of Hospitalizations for Tick-Borne Diseases in the United States from 2002 to 2021.Tropical medicine and infectious disease · 2025Article
- 'You adapt, and you try not to resent it': a qualitative study exploring impacts of living with ticks and barriers to adopting preventive measures in Canada.BMC public health · 2025Article
- Reappraisal of the Dilution and Amplification Effect Framework: A Case Study in Lyme Disease.Ecology and evolution · 2025Review
- Review of Molecular Tools Used in Diagnosis ofAnimals : an open access journal from MDPI · 2025Review
- Dynamics ofApplied and environmental microbiology · 2025Article
- TICKHUNTER: A Targeted Hybridization-Capture Sequencing Approach for the Detection and Characterization of Tick-borne Pathogens and Blood Meals.bioRxiv : the preprint server for biology · 2025Article
- Abundance of ticks and tick-borne pathogens in domestic gardens in Belgium, 2020-2022: a citizen science approach.BMC public health · 2025Article
- Modelling the impact of climate and the environment on the spatiotemporal dynamics of Lyme borreliosis in Germany.EBioMedicine · 2025Article
75 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Lyme disease is the most common tick-borne disease in temperate regions of North America, Europe and Asia, and the number of reported cases has increased in many regions as landscapes have been altered. Although there has been extensive work on the ecology and epidemiology of this disease in both Europe and North America, substantial uncertainty exists about fundamental aspects that determine spatial and temporal variation in both disease risk and human incidence, which hamper effective and efficient prevention and control. Here we describe areas of consensus that can be built on, identify areas of uncertainty and outline research needed to fill these gaps to facilitate predictive models of disease risk and the development of novel disease control strategies. Key areas of uncertainty include: (i) the precise influence of deer abundance on tick abundance, (ii) how tick populations are regulated, (iii) assembly of host communities and tick-feeding patterns across different habitats, (iv) reservoir competence of host species, and (v) pathogenicity for humans of different genotypes of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.