Evidence map›Paper›PMID 28438890›Full record

ArticleThe EMBO journal2017

Short FtsZ filaments can drive asymmetric cell envelope constriction at the onset of bacterial cytokinesis.

Qing Yao, Andrew I Jewett, Yi-Wei Chang, Catherine M Oikonomou, Morgan Beeby, Cristina V Iancu, Ariane Briegel, Debnath Ghosal, Grant J Jensen

Abstract read
In one paragraph

Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 56 citations in OpenAlex.

  1. Combining live fluorescence imaging with in situ cryoelectron tomography sheds light on the septation process inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. The cell envelope ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. FtsZ dynamics in bacterial division: What, how, and why?Current opinion in cell biology · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Bacterial cell division at a glance.Journal of cell science · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Movement dynamics of divisome proteins and PBP2x:FtsW in cells ofProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Qing YaoDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Andrew I JewettDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Yi-Wei ChangDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Catherine M OikonomouDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Morgan BeebyDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Cristina V IancuDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Ariane BriegelDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0003-3733-3725
Debnath GhosalDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Grant J JensenDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA jensen@caltech.edu.ORCID 0000-0003-1556-4864
California Institute of Technology · US

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

FtsZ, the bacterial homologue of eukaryotic tubulin, plays a central role in cell division in nearly all bacteria and many archaea. It forms filaments under the cytoplasmic membrane at the division site where, together with other proteins it recruits, it drives peptidoglycan synthesis and constricts the cell. Despite extensive study, the arrangement of FtsZ filaments and their role in division continue to be debated. Here, we apply electron cryotomography to image the native structure of intact dividing cells and show that constriction in a variety of Gram-negative bacterial cells, including

Indexed as

CytokinesisProtein MultimerizationBacterial ProteinsCaulobacter crescentusCell WallCryoelectron MicroscopyCytoskeletal ProteinsElectron Microscope TomographyPeptidoglycanProteus mirabilisBacterial ProteinsCytoskeletal ProteinsFtsZ protein, BacteriaPeptidoglycanasymmetric divisionbacterial cell divisionCaulobacter crescentuselectron cryotomographyFtsZ

Identifiers

PMID28438890
PMCPMC5452018
OpenAlexW2608583520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.