Evidence map›Paper›PMID 28438875›Full record

ArticleIn vivo (Athens, Greece)

A New Prognostic Instrument Specifically Designed for Patients Irradiated for Recurrent Carcinoma of the Bladder.

Lisa Manig, Stefan Janssen, Steven E Schild, Dirk Rades

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lisa ManigDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Stefan JanssenDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Steven E SchildDepartment of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, U.S.A.
Dirk RadesDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany rades.dirk@gmx.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTo develop an instrument that could estimate the 1-year survival probabilities of patients irradiated for recurrent carcinoma of the bladder. PATIENTS AND

methodsThirty patients irradiated for locally recurrent bladder carcinoma were included. Six pre-treatment factors [age, gender, Karnofsky score (KPS), pack years, grading and time between cancer diagnosis and radiotherapy] were evaluated for survival. Of those factors showing a trend or significance on multivariate analysis, 1-year survival rates were added.

resultsOn multivariate analysis, KPS was significant (hazard ratio(HR)=3.76, p=0.008), age showed a trend (HR=2.04, p=0.13). Patient scores were five, nine, ten or fourteen points with 1-year survival rates of 13%, 25%, 57% and 82% (p=0.003). Three groups were designed, A (5-9 points), B (10 points) and C (14 points) with 1-year survival rates of 17%, 57% and 82% (p=0.001).

conclusionThis score, including three groups with different 1-year survival probabilities, can aid physicians treating patients with recurrent bladder carcinoma.

Indexed as

AgedCarcinomaFemaleHumansKarnofsky Performance StatusMaleMultivariate AnalysisNeoplasm Recurrence, LocalPrognosisSurvival RateUrinary BladderUrinary Bladder NeoplasmsirradiationLocally recurrent carcinoma of the bladderpredictive scorepre-treatment factorssurvival

Identifiers

PMID28438875
PMCPMC5461457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.