ArticleIn vivo (Athens, Greece)
Maximum Diameter and Number of Tumors as a New Prognostic Indicator of Colorectal Liver Metastases.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Evaluation of efficacy and safety of external beam radiotherapy in patients with colorectal cancer liver metastases.Discover oncology · 2026Article
- The Usefulness of Total Tumor Volume as a Prognostic Factor and in Selecting the Optimal Treatment Strategy of Chemotherapeutic Intervention in Patients with Colorectal Liver Metastases.Annals of surgical oncology · 2023Article
- Complications associated with iliosacral lymphadenectomy in dogs with metastatic apocrine gland anal sac adenocarcinoma.The Canadian veterinary journal = La revue veterinaire canadienne · 2022Article
- Multiparameter MRI-based radiomics for preoperative prediction of extramural venous invasion in rectal cancer.European radiology · 2022Article
- Total tumour volume as a prognostic factor in patients with resectable colorectal cancer liver metastases.BJS open · 2020Article
- Prognostic value of preoperative carcinoembryonic antigen/tumor size in rectal cancer.World journal of gastroenterology · 2019Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical resection is currently considered the only potentially curative option as a treatment strategy of colorectal liver metastases (CRLM). However, the criteria for selection of resectable CRLM are not clear. The aim of this study was to confirm a new prognostic indicator of CRLM after hepatic resection. PATIENTS AND
methodsOne hundred thirty nine patients who underwent initial surgical resection from 1994 to 2015 were investigated retrospectively. Prognostic factors of overall survival including the product of maximum diameter and number of metastases (MDN) were analyzed.
resultsPrimary tumor differentiation, vessel invasion, lymph node (LN) metastasis, non-optimally resectable metastases, H score, grade of liver metastases, resection with non-curative intent and MDN were found to be prognostic factors of overall survival (OS). In multivariate analyses of clinicopathological features associated with OS, MDN and non-curative intent were independent prognostic factors. Patients with MDN ≥30 had shown significantly poorer prognosis than patients with MDN <30 in OS and relapse-free survival (RFS).
conclusionMDN ≥30 is an independent prognostic factor of survival in patients with CRLM and optimal surgical criterion of hepatectomy for CRLM.
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