Evidence map›Paper›PMID 28438752›Full record

ArticleBMJ case reports2017

IgG4-related disease presenting as posterior scleritis and vitritis, progressing to multifocal orbital involvement.

Gavin L Reynolds, Jonathan H Norris, Sher Aslam, Srilakshmi Sharma

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. IgG4-related orbital disease - An update.Indian journal of ophthalmology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. A clinicopathological study on IgG4-related ophthalmic disease.International journal of ophthalmology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gavin L ReynoldsOxford Eye Hospital, John Radcliffe Hospital, Oxford, UK.
Jonathan H NorrisOxford Eye Hospital, John Radcliffe Hospital, Oxford, UK.
Sher AslamOxford Eye Hospital, John Radcliffe Hospital, Oxford, UK.
Srilakshmi SharmaOxford Eye Hospital, John Radcliffe Hospital, Oxford, UK.
John Radcliffe Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgG4-related disease (IgG4-RD) is a rare, chronic inflammatory condition that may involve nearly every organ system. Originally identified as a cause of autoimmune pancreatitis, its characteristic histological and clinical features have been found in a wide variety of inflammatory presentations, including the eye and orbit. Here we describe an example of a case of IgG4-RD initially presenting as scleritis and vitritis, with further progression to multifocal bilateral orbital involvement. Tissue biopsy of an orbital mass was highly characteristic of IgG4-RD histology and a rapid clinical response to corticosteroids was observed. This case highlights IgG4-RD as a rare cause of intraocular inflammation that may progress to involve the orbit.

Indexed as

Adrenal Cortex HormonesAged, 80 and overBiopsyDiagnosis, DifferentialDisease ProgressionFemaleHumansImmunoglobulin GOrbital DiseasesScleritisVitreous BodyAdrenal Cortex HormonesImmunoglobulin GImmunologyOphthalmologyRetinaRheumatology

Identifiers

PMID28438752
PMCPMC5534934
OpenAlexW2608748483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.