Evidence map›Paper›PMID 28438526›Full record

ReviewAlcohol (Fayetteville, N.Y.)2017

Emerging roles for ncRNAs in alcohol use disorders.

R Dayne Mayfield

Open access · greenAbstract readReview
In one paragraph

Review in Alcohol (Fayetteville, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  9. Article
  10. RNA biomarkers for alcohol use disorder.Frontiers in molecular neuroscience · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

R Dayne MayfieldWaggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address: dayne.mayfield@austin.utexas.edu.
The University of Texas at Austin · US

Funding

GENE EXPRESSION IN THE HUMAN ALCOHOLIC BRAINR01AA012404 · NIAAA · UNIVERSITY OF TEXAS AUSTIN · PI MAYFIELD, ROY DAYNE · 2000 to 2025
$10.7M
Next Generation Sequencing of Human Alcoholic BrainU01AA020926 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI Roy DAYNE MAYFIELD · 2011 to 2026
$6.7M
Novel molecular and cellular approaches for alcoholism medication developmentP01AA020683 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI HARRIS, ROBERT A · 2012 to 2016
$3.3M
NIAAA NIH HHS P01 AA020683NIAAA NIH HHS R01 AA012404NIAAA NIH HHS U01 AA020926
6 · The paper itself

Abstract

Chronic alcohol exposure produces widespread neuroadaptations and alterations in gene expression in human alcoholics and animal models. Technological advances in the past decade have increasingly highlighted the role of non-protein-coding RNAs (ncRNAs) in the regulation of gene expression and function. These recently characterized molecules were discovered to mediate diverse processes in the central nervous system, from normal development and physiology to regulation of disease, including alcoholism and other psychiatric disorders. This review will investigate the recent studies in human alcoholics and rodent models that have profiled different classes of ncRNAs and their dynamic alcohol-dependent regulation in brain.

Indexed as

Alcohol DrinkingAlcoholismAnimalsBrainGene Expression RegulationHumansMicroRNAsRNA, Long NoncodingMicroRNAsRNA, Long NoncodingAlcoholGene regulationLong noncoding RNAmicroRNANext generation sequencingNon-coding RNATranscriptome

Identifiers

PMID28438526
PMCPMC5504532
OpenAlexW2607367245

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.