Evidence map›Paper›PMID 28438507›Full record

ArticleEBioMedicine2017

Cardiothoracic Transplant Recipient Mycoplasma hominis: An Uncommon Infection with Probable Donor Transmission.

Rahul Sampath, Robin Patel, Scott A Cunningham, Sana Arif, Richard C Daly, Andrew D Badley, Mark E Wylam

Open access · goldAbstract readCase Reports
In one paragraph

Article in EBioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Postoperative DisseminatedInfection and drug resistance · 2025
    Article
  5. Donor-derived Mycoplasma and Ureaplasma infections in lung transplant recipients: A prospective study of donor and recipient respiratory tract screening and recipient outcomes.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  6. Article
  7. Accurate etiological diagnosis ofJournal of thoracic disease · 2024
    Article
  8. Risk factors, management, and clinical outcomes of invasive Mycoplasma and Ureaplasma infections after lung transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  9. Routine Donor and Recipient Screening forOpen forum infectious diseases · 2022
    Article
  10. Hyperammonemia in lung transplant patients and its management: a review.Indian journal of thoracic and cardiovascular surgery · 2022
    Review
  11. Article
  12. Article
  13. Lung Abscess and Recurrent Empyema After Infection WithOpen forum infectious diseases · 2022
    Article
  14. Article
  15. [Clinical implications of the genus Mycoplasma].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Review
  16. Tetracycline Resistance Mediated byAntimicrobial agents and chemotherapy · 2021
    Article
  17. IDCases · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rahul SampathDivision of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Robin PatelDivision of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA; Clinical Microbiology Laboratory, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Scott A CunninghamClinical Microbiology Laboratory, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Sana ArifDuke University Medical School, Durham, NC 27708, USA.
Richard C DalyCardiovascular Surgery, Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Andrew D BadleyDivision of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Mark E WylamDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Rochester, MN 55905, USA. Electronic address: wylam.mark@mayo.edu.
Mayo Clinic · USDuke University · USMayo Clinic in Arizona · US

Funding

Prime shock and kill for HIV erradicationR01AI110173 · NIAID · MAYO CLINIC ROCHESTER · PI BADLEY, ANDREW D · 2014 to 2024
$6.9M
Evaluating the role of the novel apoptosis inhibitor TRAILshort, in maintaining HIV persistence.R01AI120698 · NIAID · MAYO CLINIC ROCHESTER · PI BADLEY, ANDREW D · 2015 to 2019
$2.5M
NIAID NIH HHS R01 AI110173NIAID NIH HHS R01 AI120698
6 · The paper itself

Abstract

The role of infection with Mycoplasma hominis following cardiothoracic organ transplantation and its source of transmission have not been well-defined. Here, we identify and describe infection with M. hominis in patients following cardiothoracic organ transplantation after reviewing all cardiothoracic transplantations performed at our center between 1998 and July 2015. We found seven previously unreported cases of M. hominis culture positive infection all of whom presented with pleuritis, surgical site infection, and/or mediastinitis. PCR was used to establish the diagnosis in four cases. In two instances, paired single lung transplant recipients manifested infection, and in one of these pairs, isolates were indistinguishable by multilocus sequence typing (MLST). To investigate the prevalence of M. hominis in the lower respiratory tract, we tested 178 bronchoalveolar lavage (BAL) fluids collected from immunocompromised subjects for M. hominis by PCR; all were negative. Review of the literature revealed an additional 15 cases of M. hominis in lung transplant recipients, most with similar clinical presentations to our cases. We recommend that M. hominis should be considered in post-cardiothoracic transplant infections presenting with pleuritis, surgical site infection, or mediastinitis. M. hominis PCR may facilitate early diagnosis and prompt therapy. Evaluation for possible donor transmission should be considered.

Indexed as

Heart TransplantationLung TransplantationMycoplasma hominisAdolescentAdultAgedFemaleHumansMaleMiddle AgedMycoplasma InfectionsTissue DonorsTransplant RecipientsYoung AdultCardiothoracic transplantationInfectionMycoplasma hominis

Identifiers

PMID28438507
PMCPMC5440619
OpenAlexW2606783611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.