Evidence map›Paper›PMID 28438415›Full record

ArticleOphthalmology2017

Immediate Sequential vs. Delayed Sequential Bilateral Cataract Surgery: Retrospective Comparison of Postoperative Visual Outcomes.

Lisa J Herrinton, Liyan Liu, Stacey Alexeeff, James Carolan, Neal H Shorstein

Registry-linked trialOpen access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05069753 (Patient Reported Visual Function Outcome Following Bilateral Cataract Surgery), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05069753 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Patient Reported Visual Function Outcome Following Bilateral Cataract Surgery

TypeinterventionalSponsorRigshospitalet, DenmarkRan2021 to 2022Enrolled300ConditionsBilateral Cataract, Charles Bonnet SyndromeArmsImmediate sequential bilateral cataract surgery (ISBCS), Delayed sequential bilateral cataract surgery (DSBCS)
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Recent trends and outcomes in immediate and delayed sequential bilateral cataract surgeries: a nationwide cohort study in South Korea.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
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  6. Observational
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  8. Preoperative Blood Transfusion Requirements for Hemorrhoidal Severe Anemia: A Retrospective Study of 128 Patients.Medical science monitor : international medical journal of experimental and clinical research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lisa J HerrintonDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Liyan LiuDivision of Research, Kaiser Permanente Northern California, Oakland, California.
Stacey AlexeeffDivision of Research, Kaiser Permanente Northern California, Oakland, California.
James CarolanDepartment of Ophthalmology, Kaiser Permanente San Rafael, San Rafael, California.
Neal H ShorsteinDepartments of Ophthalmology and Quality, Kaiser Permanente, Walnut Creek, California. Electronic address: nshorstein@eyeonsight.org.
Kaiser Permanente · USKaiser Permanente San Rafael Medical Center · USKaiser Permanente Walnut Creek Medical Center · US

Funding

Predicting final visual acuity following cataract surgeryR01EY027329 · NEI · KAISER FOUNDATION RESEARCH INSTITUTE · PI HERRINTON, LISA J · 2017 to 2018
$743k
Comparative Effectiveness of Prophylaxis in Cataract SurgeryR21EY022989 · NEI · KAISER FOUNDATION RESEARCH INSTITUTE · PI HERRINTON, LISA J · 2013 to 2014
$432k
NEI NIH HHS R01 EY027329NEI NIH HHS R21 EY022989
6 · The paper itself

Abstract

objectiveWe conducted a retrospective comparative-effectiveness study of best-corrected visual acuity (BCVA) and refractive error (RE) after immediate sequential (ISBCS) and delayed sequential (DSBCS) bilateral cataract surgery. We tested 2 hypotheses: (1) among DSBCS patients, second-eye outcomes were no different than first-eye outcomes; (2) averaged between each patient's 2 eyes, outcomes did not differ between ISBCS and DSBCS patients.

designRetrospective comparative-effectiveness study.

participantsKaiser Permanente Northern California members who underwent noncomplex bilateral cataract surgery from January 1, 2013, through June 30, 2015.

methodsWe performed an intention-to-treat analysis comparing ISBCS to DSBCS using conditional logistic regression analysis, accounting for surgeon and patient-level factors.

main outcome measuresBCVA, RE.

resultsThe analysis of visual outcomes included both eyes of 13 711 DSBCS and 3561 ISBCS patients. Because of the large sample size, some statistical differences lacked clinical significance. Ocular comorbidities were slightly more prevalent in DSBCS patients. Postoperative BCVA was 20/20 or better in 48% of DSBCS first eyes, 49% of DSBCS second eyes, 53% of ISBCS right eyes, and 51% of ISBCS left eyes. The within-person difference in postoperative BCVA averaged zero (0.00) between the first and second DSBCS eyes, and between the ISBCS right and left eyes. After adjustment, average postoperative BCVA was better in ISBCS patients, although the difference was not statistically significant (compared with 20/20 or better: odds ratio for worse than 20/20 was 0.91, 95% confidence interval 0.83-1.01). Emmetropia (spherical equivalent -0.5 to 0 diopter) was achieved in 61% of first DSBCS eyes, 61% of second DSBCS eyes, 63% of ISBCS right eyes, and 63% of ISBCS left eyes. After adjustment, average postoperative RE was no different in ISBCS compared with DSBCS patients (compared with emmetropia: odds ratio for ametropia was 1.02, confidence interval 0.92-1.12). We confirmed 1 case of postoperative endophthalmitis in 10 494 ISBCS eyes (1.0 per 10 000 eyes) and 2 cases in 38 736 DSBCS eyes (0.5 per 10 000 eyes) (P = 0.6), and no patient had bilateral endophthalmitis.

conclusionsCompared with DSBCS, we found no evidence that ISBCS was associated with worse postoperative BCVA or RE, or with an increased complication risk.

Indexed as

Lens Implantation, IntraocularAgedAged, 80 and overBiometryCaliforniaFemaleHumansMaleManaged Care ProgramsPhacoemulsificationPostoperative PeriodPseudophakiaRefractive ErrorsRetrospective StudiesTreatment OutcomeVisual Acuity

Identifiers

PMID28438415
PMCPMC5531866
OpenAlexW2606474485

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.