ReviewTrends in genetics : TIG2017
Developmental and Transmittable Origins of Obesity-Associated Health Disorders.
Review in Trends in genetics : TIG, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Gonadotropin response to insulin and lipid infusion reproduces the reprometabolic syndrome of obesity in eumenorrheic lean women: a randomized crossover trial.Fertility and sterility · 2021Trial
- m6A-Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Persistent effects of pre-differentiation manganese exposure on adipogenesis and metabolic function in differentiated 3T3-L1 adipocyte cells.Journal of hazardous materials advances · 2026Article
- Generation of human appetite-regulating neurons and tanycytes from pluripotent stem cells.Cell stem cell · 2026Article
- Maternal omega-6 to omega-3 conversion reduces osteoarthritis pain-related behaviors in adult female offspring.Arthritis research & therapy · 2026Article
- Addressing Childhood Malnutrition in Europe: Policy Approaches to Promote Healthy Eating in Young Children.Children (Basel, Switzerland) · 2026Review
- Grandmaternal perinatal serum polychlorinated biphenyls and prevalence of obesity in adult daughters and granddaughters.Obesity (Silver Spring, Md.) · 2025Article
- Maternal high-fat high-sugar diet impairs bone quality and strength but not cartilage in aging mice.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- DNA methylation in cord blood partially mediates the effects of prepregnancy BMI on early childhood offspring BMI.Obesity (Silver Spring, Md.) · 2025Article
- Adverse effects of gestational diabetes mellitus on fetal monocytes revealed by single-cell RNA sequencing.iScience · 2024Article
- Micronutrients in early life and offspring metabolic health programming: a promising target for preventing non-communicable diseases.European journal of clinical nutrition · 2023Review
- Mitochondrial Dysfunction in PCOS: Insights into Reproductive Organ Pathophysiology.International journal of molecular sciences · 2023Review
- Programming Mechanism of Adipose Tissue Expansion in the Rat Offspring of Obese Mothers Occurs in a Sex-Specific Manner.Nutrients · 2023Article
- Effect of Maternal Gradient Nutritional Restriction during Pregnancy on Mammary Gland Development in Offspring.Animals : an open access journal from MDPI · 2023Article
- Comparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka.Scientific reports · 2022Article
- Imbalance hepatic metabolism homeostasis in the F1 generation of endometrialFrontiers in physiology · 2022Article
- Article
- Impact of maternal gestational weight gain in twin pregnancies on early childhood obesity risk: A longitudinal birth cohort study.Frontiers in pediatrics · 2022Article
- Uncovering the important role of mitochondrial dynamics in oogenesis: impact on fertility and metabolic disorder transmission.Biophysical reviews · 2021Review
- Erectile Dysfunction in Men Burdened with the Familial Occurrence of Coronary Artery Disease.Journal of clinical medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The current global obesity pandemic is clearly linked to both the increasing prevalence of, and preference for, foods high in calories, specifically fat and sucrose, and declining levels of daily physical activity. A less commonly discussed possible explanation is that risk of obesity begins in utero as a result of developmental plasticity during early life. This idea fits into the broader Developmental Origins of Health and Diseases (DOHAD) hypothesis, which holds that stressful in utero exposure manifests as disease in adulthood. In this review, we highlight several studies that have revealed the role of epigenetics in multigenerational transmission of developmentally programmed obesity and associated cardiometabolic disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.