ArticleeLife2017
Variation in olfactory neuron repertoires is genetically controlled and environmentally modulated.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed.
- Article
- Convergent motifs of early olfactory processing are recapitulated by layer-wise efficient coding.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- Stable olfactory receptor activation across odor complexity.iScience · 2025Article
- Olfactory binding proteins: a review across the Insecta.Frontiers in zoology · 2025Review
- A common mechanism of singular gene choice is revealed by broadly expressed odorant receptor transgenes within the olfactory epithelium.Cell reports · 2025Article
- Article
- New Neurons in the Postnatal Olfactory System: Functions in the Healthy and Regenerating Brain.Brain sciences · 2025Review
- Determinants of odorant receptor transcription and gene choice.Chemical senses · 2025Review
- The primacy model and the structure of olfactory space.PLoS computational biology · 2024Article
- The influence of olfactory experience on the birthrates of olfactory sensory neurons with specific odorant receptor identities.Genesis (New York, N.Y. : 2000) · 2024Review
- Role of iRhom2 in Olfaction: Implications for Odorant Receptor Regulation and Activity-Dependent Adaptation.International journal of molecular sciences · 2024Article
- Article
- Adaptive olfactory circuitry restores function despite severe olfactory bulb degeneration.Current biology : CB · 2023Article
- The Role of the Stimulus in Olfactory Plasticity.Brain sciences · 2023Review
- Expanded olfactory system in ray-finned fishes capable of terrestrial exploration.BMC biology · 2023Article
- Robust odor identification in novel olfactory environments in mice.Nature communications · 2023Article
- Large-scale assessment of pros and cons of autopsy-derived or tumor-matched tissues as the norms for gene expression analysis in cancers.Computational and structural biotechnology journal · 2023Article
- Lifespan extension in female mice by early, transient exposure to adult female olfactory cues.eLife · 2022Article
- Efficient information coding and degeneracy in the nervous system.Current opinion in neurobiology · 2022Review
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
The mouse olfactory sensory neuron (OSN) repertoire is composed of 10 million cells and each expresses one olfactory receptor (OR) gene from a pool of over 1000. Thus, the nose is sub-stratified into more than a thousand OSN subtypes. Here, we employ and validate an RNA-sequencing-based method to quantify the abundance of all OSN subtypes in parallel, and investigate the genetic and environmental factors that contribute to neuronal diversity. We find that the OSN subtype distribution is stereotyped in genetically identical mice, but varies extensively between different strains. Further, we identify
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.