Evidence map›Paper›PMID 28438185›Full record

Trial reportTrials2017

Comparison of the efficacy between conventional moxibustion and smoke-free moxibustion on knee osteoarthritis: study protocol of a randomized controlled trial.

Lin-Lin Zhu, Jian-Ying Zhou, Ling Luo, Xiang Wang, Jia-Xi Peng, Sha-Sha Chen, Hai-Yan Yin, Qiao-Feng Wu, Cheng-Shun Zhang, Peng Lv and 2 more

Registry-linked trialOpen access · goldAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02772055 (A Multicentre, Randomised, Single Blinded, Parallel-group Study of Moxa Smoke Effect in Moxibustion Treating Knee Osteoarthritis), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02772055 nacompletednot on this map

A Multicentre, Randomised, Single Blinded, Parallel-group Study of Moxa Smoke Effect in Moxibustion Treating Knee Osteoarthritis

TypeinterventionalSponsorChengdu University of Traditional Chinese MedicineRan2016 to 2019Enrolled138ConditionsPainArmsMoxibustion, Moxa smoke purification device
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Lin-Lin ZhuChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Jian-Ying ZhouChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Ling LuoChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Xiang WangChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Jia-Xi PengChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Sha-Sha ChenChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Hai-Yan YinChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Qiao-Feng WuChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Cheng-Shun ZhangChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Peng LvChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China.
Yong TangChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China. tangyong@cdutcm.edu.cn.
Shu-Guang YuChengdu University of Traditional Chinese Medicine Chengdu, Sichuan, China. ysg@cdutcm.edu.cn.
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConventional moxibustion is a representative non-drug intervention in traditional Chinese medicine, and it has been reported to produce encouraging results and benefits in relieving symptoms and improving the quality of life for patients with knee osteoarthritis (KOA) in previous clinical trials and systematic reviews. Given that increasing concerns on the safety of generated smoke from conventional moxibustion have received much attention, smoke-free moxibustion is regarded as a potential alternative. However, whether smoke-free moxibustion would display a similar efficacy to that of conventional moxibustion still remains unclear. Therefore, this randomized controlled trial attempts to investigate the difference of efficacy between conventional moxibustion and smoke-free moxibustion in patients with KOA. METHODS/

designThis is a multicenter, randomized, single-blinded, parallel-group clinical trial. A total of 138 eligible participants with KOA will be randomly allocated to two groups (conventional moxibustion group and smoke-free moxibustion group) in seven hospitals in China. Participants will receive 12 sessions of moxibustion treatment at three acupoints (EX-LE4, ST35, and ST36) over a period of 4 weeks (3 sessions per week). A smoke-removing device is placed at the top of the moxibustion device for the smoke-free moxibustion group (n = 69), while the conventional moxibustion group (n = 69) is treated with traditional moxibustion. The primary outcome measure will be the change of the global scale of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) from the baseline to 4 weeks. Secondary outcomes include the visual analog scale VASand Patient Global Assessment scores. Follow-up measurements will be performed on the 8th and 12th weeks after random allocation. DISCUSSION: This study will contribute to providing a solid foundation for the selection of moxibustion in clinical application as well as future research in moxibustion therapy.

trial registrationClinicalTrials.gov, NCT02772055 . Registered on 12 May 2016.

Indexed as

Acupuncture PointsAdultAgedBiomechanical PhenomenaChinaClinical ProtocolsComparative Effectiveness ResearchDisability EvaluationFemaleHumansKnee JointMaleMiddle AgedMoxibustionOsteoarthritis, KneeRecovery of FunctionKnee osteoarthritisMoxa smokeMoxibustionProtocolRandomized controlled trial

Identifiers

PMID28438185
PMCPMC5402673
OpenAlexW2609872729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.