Evidence map›Paper›PMID 28438173›Full record

ArticleJournal of translational medicine2017

Preliminary results demonstrating the impact of Mediterranean diet on bone health.

Maria Cristina Savanelli, Luigi Barrea, Paolo Emidio Macchia, Silvia Savastano, Andrea Falco, Andrea Renzullo, Elisabetta Scarano, Immacolata Cristina Nettore, Annamaria Colao, Carolina Di Somma

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
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  16. Observational
  17. Eat, breathe, sleep with Osteogenesis Imperfecta.Orphanet journal of rare diseases · 2021
    Article
  18. Observational
  19. Review
  20. Mediterranean Diet In Healthy Aging.The journal of nutrition, health & aging · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Maria Cristina SavanelliI.O.S. & COLEMAN Srl, Acerra, 80011, Naples, Italy.
Luigi BarreaI.O.S. & COLEMAN Srl, Acerra, 80011, Naples, Italy.
Paolo Emidio MacchiaDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Napoli, Via Sergio Pansini 5, 80131, Naples, Italy. pmacchia@unina.it.ORCID 0000-0001-6503-6942
Silvia SavastanoDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Napoli, Via Sergio Pansini 5, 80131, Naples, Italy.
Andrea FalcoI.O.S. & COLEMAN Srl, Acerra, 80011, Naples, Italy.
Andrea RenzulloDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Napoli, Via Sergio Pansini 5, 80131, Naples, Italy.
Elisabetta ScaranoDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Napoli, Via Sergio Pansini 5, 80131, Naples, Italy.
Immacolata Cristina NettoreDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Napoli, Via Sergio Pansini 5, 80131, Naples, Italy.
Annamaria ColaoDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Napoli, Via Sergio Pansini 5, 80131, Naples, Italy.
Carolina Di SommaIRCCS SDN, Napoli Via Gianturco 113, 80143, Naples, Italy.
Federico II University Hospital · ITSDN Istituto di Ricerca Diagnostica e Nucleare · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNutrition is an environmental factor affecting bone health. Nutrition is considered essential to achieve and maintain optimal bone mass. Mediterranean diet (MD) has shown to prevent bone disease. Aim of this study is to investigate the relationship between bone health status and adherence the MD.

methodsFour-hundred eighteen healthy people (105 males and 313 females, age 50 ± 14 years) were recruited in the outdoor hospital of the "Campus Salute Onlus" held in Piazza del Plebiscito in Naples, October 17-20th 2013 and 09-11th October 2014. All subjects underwent clinical assessment, calcaneal quantitative ultrasound (QUS) scanner and PREvención con DIeta MEDiterránea (PREDIMED) questionnaire.

resultsGlobally, prevalence of osteoporosis and osteopenia were 7.7 and 46.0%, respectively. The majority of subjects (60.5%) had an average score (score 6-9) of adherence to MD. The T-score showed positive correlation with PREDIMED score (r = 0.250, p < 0.001). The higher T-scores were positively associated with a higher consumption of extra-virgin olive oil (EVOO), vegetables, fruits, legumes, and fish and negatively associated with consumption of red meat. The higher T-scores were positively associated with the highest odds of PREDIMED scores (higher adherence) (OR 6.91, IC 6.27-7.61, p < 0.001). Multiple regression analysis models indicated that, among the single food items investigated, high T-score can be predicted by consumption of EVOO (p < 0.001), fish (p < 0.001) and fruit (p = 0.002) intake. A PREDIMED score of 3 was found to be predictive for a low T-score (α = 0.05, R-squared index = 0.417).

conclusionsThe results demonstrate a positive correlation between bone health status and adherence to MD, suggesting that a high adherence to MD promotes bone health. The observations here reported confirmed that a specific dietary approach, such as MD, can represent a modifiable environmental factor for osteoporosis' prevention.

Indexed as

Diet, MediterraneanAnthropometryBone and BonesBone Diseases, MetabolicFemaleHumansLogistic ModelsMaleMiddle AgedOdds RatioOsteoporosisPrevalenceBone healthCalcaneal quantitative ultrasound (QUS) scannerEnvironmental factorsImaging techniquesMediterranean diet

Identifiers

PMID28438173
PMCPMC5404307
OpenAlexW2607579504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.