Evidence map›Paper›PMID 28438158›Full record

ArticleBMC public health2017

Prevalence of helicobacter pylori infection among children living in a rural setting in Sub-Saharan Africa.

Yaw Asante Awuku, David Larbi Simpong, Ishmael Kunateh Alhassan, Derek Anamaale Tuoyire, Taiba Afaa, Patrick Adu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05861687 (Comparative Recurrence Rate Investigation of Esomeprazole Versus Lansoprazole in Triple-Combination Therapy to Eradicate Helicobacter Pylori Infection Among Pediatrics), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05861687 phase2 / phase3completednot on this mapstarted 2021, after this paper: background citation

Comparative Recurrence Rate Investigation of Esomeprazole Versus Lansoprazole in Triple-Combination Therapy to Eradicate Helicobacter Pylori Infection Among Pediatrics: Multicentre, Randomized, and Controlled Trials

TypeinterventionalSponsorFinni KollinsRan2021 to 2022Enrolled51ConditionsHelicobacter Pylori InfectionArmsEsomeprazole, Lansoprazole, Amoxicillin, Clarithromycin
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

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  12. Sero- and Feco-Prevalence ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
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  13. Worldwide Prevalence and Risk Factors ofChildren (Basel, Switzerland) · 2022
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  16. Association betweenFrontiers in endocrinology · 2022
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  17. Prevalence ofJournal of tropical medicine · 2021
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  18. Concurrent infection of intestinal parasites andParasite epidemiology and control · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yaw Asante AwukuDepartment of Medicine and Therapeutics, University of Cape Coast, Cape Coast, Ghana. ppawuku@gmail.com.
David Larbi SimpongDepartment of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana.
Ishmael Kunateh AlhassanDepartment of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana.
Derek Anamaale TuoyireDepartment of Community Medicine, Universty of Cape Coast, Cape Coast, Ghana.
Taiba AfaaDepartment of Child Health, University of Ghana, Accra, Ghana.
Patrick AduDepartment of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana.
University of Cape Coast · GHUniversity of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHelicobacter pylori infection affects more than half of the world's population. It is generally acquired during childhood with no symptoms but has long- term clinical sequelae. This study estimated the prevalence of H. pylori infection amongst children in a rural environment in Africa.

methodsWe conducted a cross-sectional study over a four (4)-month period within two rural communities. 240 asymptomatic children were tested using lateral flow immunochromatographic assay for the qualitative detection of H. pylori antigen in a fecal specimen. Statistical analysis and processing was done using Stata version 11.

resultsThe mean age of the participants was 10.5 ± 2.7 years with the predominant age range being 8-10 years (34.6%), and a mean household size of 7.1 ± 1.7. The study population showed a female preponderance of 57.1%. 88% of the H. pylori positive children lacked pipe and borehole drinking water. All of the positive H. pylori children practiced open-air defecation. The overall prevalence of H. pylori infection among children in this study was at least 14.2%.

conclusionOur study demonstrated a high prevalence of H. pylori infection among children in a rural setting. Educational status of parents did not affect H. pylori prevalence but increasing household numbers, female gender, source of drinking water other than pipe and borehole, open-air defecation and younger age were associated with a higher H. pylori prevalence.

Indexed as

Helicobacter pyloriAfrica South of the SaharaChildCross-Sectional StudiesFemaleHelicobacter InfectionsHumansMalePrevalenceRisk FactorsRural PopulationWater SupplyChildren and GhanaH.pylori infectionImmune chromatographic assayPrevalence

Identifiers

PMID28438158
PMCPMC5404296
OpenAlexW2608890228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.