Evidence map›Paper›PMID 28438142›Full record

ArticleBMC ophthalmology2017

Α molecular epidemiological analysis of adenoviruses from excess conjunctivitis cases.

A Balasopoulou, P Κokkinos, D Pagoulatos, P Plotas, O E Makri, C D Georgakopoulos, A Vantarakis

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 54 citations in OpenAlex.

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  14. Literature Review on Health Emigration in Rare Diseases-A Machine Learning Perspective.International journal of environmental research and public health · 2023
    Review
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

A BalasopoulouEnvironmental Microbiology Unit, Department of Public Health, Medical School, University of Patras, Patras, Greece.
P ΚokkinosEnvironmental Microbiology Unit, Department of Public Health, Medical School, University of Patras, Patras, Greece.
D PagoulatosDepartment of Ophthalmology, Medical School, University of Patras, Patras, Greece.
P PlotasDepartment of Ophthalmology, Medical School, University of Patras, Patras, Greece.
O E MakriDepartment of Ophthalmology, Medical School, University of Patras, Patras, Greece.
C D GeorgakopoulosDepartment of Ophthalmology, Medical School, University of Patras, Patras, Greece.
A VantarakisEnvironmental Microbiology Unit, Department of Public Health, Medical School, University of Patras, Patras, Greece. avanta@upatras.gr.
University of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundΤo perform a molecular epidemiological analysis of viral conjunctivitis among excess conjunctivitis cases recorded at the University Hospital of Patras, Greece, for the period March to June 2012.

methodsA structured questionnaire containing demographic and clinical data was developed in order to collect retrospective data on the cases. Eye swab specimens were collected and molecular detection of adenoviruses was performed by nested PCR. Positive results were confirmed by sequencing. To determine the relatedness between the isolated sequences, a phylogenetic analysis was conducted.

resultsThe epidemiological analysis (including retrospective data) included 231 conjunctivitis cases (47.1% male, and 52.8% female). Based on clinical features 205 of the cases were diagnosed of viral origin (46.3% male and 53.7% female), 4 of bacterial origin (50% male and 50% female) while 22 were undefined conjunctivitis. The outbreak excess cases (included 156 cases) affected all age groups regardless gender predilection. For the positive samples indicated that 29 samples (72.5%) were AdV17, and 5 (12.5%) as AdV54.

conclusionsMolecular analysis could define the cause of viral conjunctivitis, while epidemiological data contributed to the assessment of the risk factors and underlined possible preventive measures. This study is one of the very few on viral conjunctivitis in Greece. This outbreak underscores the need for a national surveillance system for acute infectious conjunctivitis outbreaks. The epidemiological as well as molecular investigation on HAdV ocular infections is rather absent in Greece, which has no surveillance system for viral conjunctivitis.

Indexed as

Disease OutbreaksAdenoviridaeAdenovirus Infections, HumanAdolescentAdultAgedAged, 80 and overChildChild, PreschoolConjunctivitis, ViralDNA, ViralEye Infections, ViralFemaleGreeceHumansIncidenceDNA, ViralAdenovirusConjunctivitisEyeInfectionMolecular detection

Identifiers

PMID28438142
PMCPMC5404675
OpenAlexW2609559153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.