ArticleBMC infectious diseases2017
Viral aetiologies of acute encephalitis in a hospital-based South Asian population.
Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 17 citations in OpenAlex.
- Dissecting Age-Stratified Immunity to Different Dengue Virus Serotypes and Zika Viruses Among Children in a Highly Endemic Region in Sri Lanka.Open forum infectious diseases · 2026Article
- Detection of dengue virus encephalitis in central part of Sri Lanka.World journal of virology · 2025Article
- Global Landscape of Encephalitis: Key Priorities to Reduce Future Disease Burden.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Review
- The Worldwide Prevalence of Herpes Simplex Virus Encephalitis and Meningitis: A Systematic Review and Meta-Analysis.Turkish archives of pediatrics · 2023Article
- Article
- Cognitive decline following acute viral infections: literature review and projections for post-COVID-19.European archives of psychiatry and clinical neuroscience · 2022Review
- Effective treatment of osmotic demyelination syndrome with plasmapheresis: a case report and review of the literature.Journal of medical case reports · 2021Review
- Analysis of the Effect of Incentive Nursing Intervention in Children with Severe Viral Encephalitis and Myocarditis during Rehabilitation Based on Diffusion Weighted MRI.Journal of healthcare engineering · 2021Article
- Identification of Immune Responses to Japanese Encephalitis Virus Specific T Cell Epitopes.Frontiers in public health · 2020Article
- Predictors of Outcome in Clinically Diagnosed Viral Encephalitis Patients: A 5-Year Prospective Study.BioMed research international · 2020Article
- Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection.Nature communications · 2018Article
- Significance of Neuronal Autoantibodies in Comparison to Infectious Etiologies among Patients Presenting with Encephalitis in a Region with a High Prevalence of Infections.Annals of Indian Academy of NeurologyArticle
- Neurological manifestations due to dengue virus infection in children: clinical follow-up.Pathogens and global healthArticle
- Herpes Simplex Virus-2 Encephalitis Complicated with Multiple Cranial Neuritis and Dysautonomia.Journal of pediatric neurosciencesArticle
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aetiological spectrum of acute encephalitis shows inter- and intra-geographical variations. We aimed to identify the viruses that cause infectious encephalitis in Sri Lanka, which represents a South Asian population.
methodsA cross-sectional study was conducted among 99 patients with encephalitis/meningoencephalitis admitted to two tertiary-care hospitals in Colombo. Cerebrospinal fluid and serum were tested for conventional and emerging encephalitogenic viruses. Specific nucleic acid amplification and antibody assays were used to identify viruses. Plaque reduction neutralization test was done to confirm the diagnosis of West Nile virus (WNV).
resultsPatients' age ranged from 1 month to 73 years (mean = 24.91; SD = 21.33) with a male:female ratio of 1.75:1. A viral aetiology was identified in only 27.3%. These included dengue virus (40.7%), Japanese encephalitis virus (25.9%), varicella zoster virus, WNV and probable Epstein Barr virus (11.1% each). None were positive for herpes simplex viruses or cytomegalovirus. Screening for bacterial aetiologies was negative for all patients. There were no distinguishable clinical or laboratory findings between the different viral aetiologies. The case fatality rate was 7%, which was higher among patients with an identified viral aetiology.
conclusionsA viral aetiology was identified in only about a quarter of patients with encephalitis. Dengue virus accounted for the majority.
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