Evidence map›Paper›PMID 28438062›Full record

SynthesisThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians2018

Associations of maternal obesity and smoking status with perinatal outcomes.

Julie K Phillips, Joan M Skelly, Sarah E King, Ira M Bernstein, Stephen T Higgins

Abstract readMeta-Analysis
In one paragraph

Synthesis in The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pregnancy and Delivery Outcomes Following Benzodiazepine Exposure: A Systematic Review and Meta-analysis.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2020
    Pooled it
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julie K Phillipsa Vermont Center on Behavior and Health , University of Vermont , Burlington , VT , USA.
Joan M Skellyc Department of Medical Biostatistics , University of Vermont , Burlington , VT , USA.
Sarah E Kingb Department of Obstetrics, Gynecology, and Reproductive Sciences , University of Vermont , Burlington , VT , USA.
Ira M Bernsteina Vermont Center on Behavior and Health , University of Vermont , Burlington , VT , USA.
Stephen T Higginsa Vermont Center on Behavior and Health , University of Vermont , Burlington , VT , USA.

Funding

Vermont Center on Behavior and HealthP20GM103644 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 2013 to 2022
$21.3M
Vermont Center on Tobacco Regulatory ScienceP50DA036114 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 2013 to 2017
$19.1M
Voucher-based incentives to treat pregnant smokersR01DA014028 · NIDA · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 2001 to 2010
$6.0M
Financial Incentives for Smoking Cessation Among Disadvantaged Pregnant WomenR01HD075669 · NICHD · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 2013 to 2017
$3.6M
NICHD NIH HHS R01 HD075669NIDA NIH HHS P50 DA036114NIDA NIH HHS R01 DA014028NIGMS NIH HHS P20 GM103644
6 · The paper itself

Abstract

Maternal obesity and smoking are associated with adverse perinatal outcomes. These prevalent conditions contribute to health disparities. In this study, we examine whether maternal BMI moderates the impact of smoking cessation on short-term perinatal outcomes. This is a secondary analysis of assessments conducted from several prospective clinical trials examining the efficacy of incentives to promote smoking cessation during pregnancy. Participants were randomly assigned to receive financial incentives contingent upon smoking abstinence or a control condition. Pregnancy outcomes were abstracted from the medical record. ANCOVA and multiple logistic regression were used for statistical analysis. Among 388 women, there was a significant interaction between maternal pre-pregnancy BMI and smoking status on gestational age at delivery (p = .03) and admission to the NICU (p = .04). Among underweight/normal weight gravidas, smoking resulted in earlier deliveries and a greater likelihood of NICU admission than in those who abstained. Among overweight/obese gravidas, there was no effect of smoking on gestational age at delivery and infants of smokers were less likely to be admitted to the NICU. Maternal obesity and smoking have significant individual effects on perinatal outcome. Maternal overweight/obesity appears to moderate the effect of smoking on gestational age at delivery and on NICU admissions.

Indexed as

Pregnancy ComplicationsFemaleHumansInfant, NewbornObesityPregnancyPremature BirthRandomized Controlled Trials as TopicRespiratory Distress Syndrome, NewbornSmokingobesityPregnancypremature birthsmokingsmoking cessation

Identifiers

PMID28438062
PMCPMC5685927

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.