SynthesisPloS one2017
Use of the MATRICS consensus cognitive battery (MCCB) to evaluate cognitive deficits in bipolar disorder: A systematic review and meta-analysis.
Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Pooled it
- Co-development of a protocol for a randomised controlled feasibility trial of CIRCuiTS™ cognitive remediation therapy for people with multiple sclerosis.Pilot and feasibility studies · 2026Review
- Effects of Deep Transcranial Magnetic Stimulation on Cognitive Function in Bipolar Depression: A Randomized Controlled Trial Using the MATRICS Consensus Cognitive Battery.Alpha psychiatry · 2026Article
- Application of cerebellar vermis theta-burst stimulation patterned repetitive transcranial magnetic stimulation in patients with chronic schizophrenia.Frontiers in psychiatry · 2025Article
- Neurocognitive function across different phases of bipolar disorder: an evaluation using the B-CATS.Frontiers in psychiatry · 2025Article
- Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study.Neuropsychiatric disease and treatment · 2025Article
- Article
- Sex-differential cognitive performance on MCCB of youth with BD-II depression.BMC psychiatry · 2024Article
- A cross-sectional study of cognitive performance in bipolar disorder across the lifespan: the cog-BD project.Psychological medicine · 2023Article
- Building a neurocognitive profile of suicidal risk in severe mental disorders.BMC psychiatry · 2022Article
- Validity of remote administration of the MATRICS Consensus Cognitive Battery for individuals with severe mental illness.Schizophrenia research. Cognition · 2022Article
- Chinese patients with hereditary spastic paraplegias (HSPs): a protocol for a hospital-based cohort study.BMJ open · 2022Article
- Do cognition and other person-level characteristics determine housing outcomes among homeless-experienced adults with serious mental illness?Psychiatric rehabilitation journal · 2021Article
- Cortical Thickness Changes in Chronic Ketamine Users.Frontiers in psychiatry · 2021Article
- Impairment in Emotional Intelligence May Be Mood-Dependent in Bipolar I and Bipolar II Disorders.Frontiers in psychiatry · 2021Article
- Familial aggregation analysis of cognitive performance in early-onset bipolar disorder.European child & adolescent psychiatry · 2020Article
- Exposure to a high dose of amoxicillin causes behavioral changes and oxidative stress in young zebrafish.Metabolic brain disease · 2020Article
- Distinct Associations of Cognitive Impairments and Reduced Gray Matter Volumes in Remitted Patients with Schizophrenia and Bipolar Disorder.Neural plasticity · 2020Article
- Article
- Amplitude of low-frequency fluctuation (ALFF) may be associated with cognitive impairment in schizophrenia: a correlation study.BMC psychiatry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Measurement and Treatment Research to Improve Cognition Schizophrenia Consensus Cognitive Battery (MCCB) has also been proposed for use in clinical trials to assess cognitive deficits in patients with bipolar disorder (BD). The aim of this study was to evaluate cognitive function assessed by the MCCB in BD.
methodsA literature search of the PubMed, Embase, PsycINFO, SCI, Cochrane Library databases and the Cochrane Controlled Trials Register was conducted. Case reports, reviews and meta-analyses were excluded and a systematic review of the remaining studies of cognitive function in BD was carried out. The cognitive outcome measure was the MCCB, including 7 domains and overall cognition. A random-effects model was applied.
resultsEighty eight studies were initially identified. Seven clinical studies comprising a total of 487 patients and 570 healthy controls (HC) were included in the meta-analysis. Patients with BD performed worse than HC in overall cognition and processing speed with a large effect size of >0.8; with a medium effect size (0.5-0.8) in attention, working memory, verbal learning and visual learning; and with a small effect size (0.2-0.5) in reasoning and problem solving and social cognition.
conclusionPatients with BD performed worse than HC in overall cognition and all cognitive domains of the MCCB. Cognitive deficits in domains of processing speed and working memory are prominent in patients with BD. Our findings suggest that MCCB can be usefully applied in BD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.