Evidence map›Paper›PMID 28437319›Full record

ArticleMedical care2017

Quality of Antiepileptic Treatment Among Older Medicare Beneficiaries With Epilepsy: A Retrospective Claims Data Analysis.

Maria Pisu, Joshua Richman, Kendra Piper, Roy Martin, Ellen Funkhouser, Chen Dai, Lucia Juarez, Jerzy P Szaflarski, Edward Faught

Abstract read
In one paragraph

Article in Medical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Treatment gaps in epilepsy.Frontiers in epidemiology · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Maria Pisu*Division of Preventive Medicine †Department of Surgery, University of Alabama at Birmingham, Birmingham, AL ‡Department of Gynecology and Obstetrics, Emory University, Atlanta, GA §Department of Neurology, University of Alabama at Birmingham, Birmingham, AL ∥Department of Neurology, Emory University, Atlanta, GA.
Joshua Richman
Kendra Piper
Roy Martin
Ellen Funkhouser
Chen Dai
Lucia Juarez
Jerzy P Szaflarski
Edward Faught
General Department of Preventive Medicine · VNUniversity of Alabama at Birmingham · USEmory University · US

Funding

Quality of Epilepsy Treatment and Costs in Older Americans by Race (QUIET CARE)R01NS080898 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PISU, MARIA · 2012 to 2014
$1.1M
NINDS NIH HHS R01 NS080898
6 · The paper itself

Abstract

backgroundEnzyme-inducing antiepileptic drugs (EI-AEDs) are not recommended for older adults with epilepsy. Quality Indicator for Epilepsy Treatment 9 (QUIET-9) states that new patients should not receive EI-AEDs as first line of treatment. In light of reported racial/ethnic disparities in epilepsy care, we investigated EI-AED use and QUIET-9 concordance across major racial/ethnic groups of Medicare beneficiaries. RESEARCH

designRetrospective analyses of 2008-2010 Medicare claims for a 5% random sample of beneficiaries 67 years old and above in 2009 augmented for minority representation. Logistic regressions examined QUIET-9 concordance differences by race/ethnicity adjusting for individual, socioeconomic, and geography factors. SUBJECTS: Epilepsy prevalent (≥1 International Classification of Disease-version 9 code 345.x or ≥2 International Classification of Disease-version 9 code 780.3x, ≥1 AED), and new (same as prevalent+no seizure/epilepsy events nor AEDs in 365 d before index event) cases. MEASURES: Use of EI-AEDs and QUIET-9 concordance (no EI-AEDs for the first 2 AEDs).

resultsCases were 21% white, 58% African American, 12% Hispanic, 6% Asian, 2% American Indian/Alaskan Native. About 65% of prevalent, 43.6% of new cases, used EI-AEDs. QUIET-9 concordance was found for 71% Asian, 65% white, 61% Hispanic, 57% African American, 55% American Indian/Alaskan new cases: racial/ethnic differences were not significant in adjusted model. Beneficiaries without neurology care, in deductible drug benefit phase, or in high poverty areas were less likely to have QUIET-9 concordant care.

conclusionsEI-AED use is high, and concordance with recommendations low, among all racial/ethnic groups of older adults with epilepsy. Potential socioeconomic disparities and drug coverage plans may affect treatment quality and opportunities to live well with epilepsy.

Indexed as

Insurance Claim ReviewMedicareQuality of Health CareAgedAged, 80 and overAnticonvulsantsEpilepsyFemaleHumansLogistic ModelsMaleRetrospective StudiesUnited StatesAnticonvulsants

Identifiers

PMID28437319
PMCPMC5487492
OpenAlexW2605419512

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.