Evidence map›Paper›PMID 28437005›Full record

ArticleThe Journal of physiology2017

Convergent ERK1/2, p38 and JNK mitogen activated protein kinases (MAPKs) signalling mediate catecholoestradiol-induced proliferation of ovine uterine artery endothelial cells.

Rosalina Villalon Landeros, Sheikh O Jobe, Gabrielle Aranda-Pino, Gladys E Lopez, Jing Zheng, Ronald R Magness

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

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  4. [ENan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
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  14. Erratum.The Journal of physiology · 2017
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rosalina Villalon LanderosDepartment of Obstetrics and Gynaecology, Perinatal Research Laboratories, University of Wisconsin-Madison, Madison, WI, USA.
Sheikh O JobeDepartment of Obstetrics and Gynaecology, Perinatal Research Laboratories, University of Wisconsin-Madison, Madison, WI, USA.
Gabrielle Aranda-PinoDepartment of Obstetrics and Gynaecology, Perinatal Research Laboratories, University of Wisconsin-Madison, Madison, WI, USA.
Gladys E LopezDepartment of Obstetrics and Gynaecology, Perinatal Research Laboratories, University of Wisconsin-Madison, Madison, WI, USA.
Jing ZhengDepartment of Obstetrics and Gynaecology, Perinatal Research Laboratories, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-2224-2372
Ronald R MagnessDepartment of Obstetrics and Gynaecology, Perinatal Research Laboratories, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-4680-5069
University of Wisconsin–Madison · US

Funding

Unified Cellular and Molecular CoreP01HD038843 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MAGNESS, RONALD R · 2001 to 2017
$14.4M
Training & Education to Advance Minorities in Science (TEAM-Science)R25GM083252 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BIRD, IAN M. · 2008 to 2021
$8.5M
Endocrinology-Reproductive Physiology Training GrantT32HD041921 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI BIRD, IAN M. · 2004 to 2022
$3.0M
ENDOTHELIUM-DERIVED VASODILATORS IN PREGNANCYR01HL049210 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAGNESS, RONALD R · 1993 to 2011
$2.6M
Physiologic Cardiovascular & Uterine eNOS Responses:Role of Endogenous EstrogenR01HL087144 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAGNESS, RONALD R · 2007 to 2010
$1.8M
Endothelial Function in a Model of IUGR Induced by Uterine Space RestrictionR01HL117341 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAGNESS, RONALD R · 2014 to 2017
$1.8M
Role of E2B Metabolites in Uterine Artery Endothelial Adaptations to PregnancyF31HD088096 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI VILLALON LANDEROS, ROSALINA · 2016 to 2017
$69k
NHLBI NIH HHS R01 HL049210NHLBI NIH HHS R01 HL087144NHLBI NIH HHS R01 HL117341NICHD NIH HHS F31 HD088096NICHD NIH HHS P01 HD038843NICHD NIH HHS T32 HD041921NIGMS NIH HHS R25 GM083252
6 · The paper itself

Abstract

key pointsThe catechol metabolites of 17β-oestradiol (E ABSTRACT: Previously we demonstrated that the biologically active metabolites of 17β-oestradiol, 2-hydroxyoestradiol (2-OHE

Indexed as

AnimalsCell ProliferationCells, CulturedEndothelial CellsEstradiolEstrogens, CatecholFemaleMitogen-Activated Protein KinasesPhosphatidylinositol 3-KinasesProtein Kinase InhibitorsSheepSignal TransductionUterine Artery2-hydroxyestradiol4-hydroxyestradiolEstradiolEstrogens, CatecholMitogen-Activated Protein KinasesPhosphatidylinositol 3-KinasesProtein Kinase Inhibitorsendothelial cellMAPKsoestrogens

Identifiers

PMID28437005
PMCPMC5509880
OpenAlexW2608733502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.