Evidence map›Paper›PMID 28436973›Full record

ArticleBone marrow transplantation2017

A review of hematopoietic cell transplantation in China: data and trends during 2008-2016.

L-P Xu, D-P Wu, M-Z Han, H Huang, Q-F Liu, D-H Liu, Z-M Sun, L-H Xia, J Chen, H-X Wang and 10 more

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07588360 (Haploidentical Combined With Cord Blood Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes), which is not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07588360 narecruitingnot on this mapstarted 2025, after this paper: background citation

Haploidentical Combined With Cord Blood Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes: A Prospective, Multicenter Clinical Study

TypeinterventionalSponsorFujian Medical University Union HospitalRan2025 to 2029Enrolled82ConditionsMDS (Myelodysplastic Syndrome), AML (Acute Myeloid Leukemia)Armshaplo-cord HSCT, Fludarabine, Cytarabine, Busulfan, Antithymocyte Globulin (ATG), Melphalan, Cyclophosphamide (CTX)
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 18 institutions in 1 country.

L-P XuPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
D-P WuThe First Affiliated Hospital of Soochow University, Soochou, China.
M-Z HanBlood Diseases Hospital, Chinese Academy of Medica, Tianjin, China.
H HuangThe First Affiliated Hospital, Zhejiang University, Hangzhou, China.
Q-F LiuNanfang Hospital, Guangzhou, China.
D-H LiuChinese PLA General Hospital, Beijing, China.
Z-M SunAnhui Provincial Hospital, Hefei, China.
L-H XiaWuhan Union Hospital, Wuhan, China.
J ChenShanghai Children's Medical Center, Shanghai, China.
H-X WangThe General Hospital of The Air Force, People's Liberation Army of China, Beijing, China.
C WangShanghai General Hospital, Shanghai, China.
C-F LiDepartment of Pediatrics, Nanfang Hospital, Guangzhou, China.
Y-R LaiThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.
J-M WangChanghai Hospital, Shanghai, China.
D-B ZhouPeking Union Medical College Hospital, Beijing, China.
H ChenThe 307th Hospital of Chinese People's Liberation Army, Beijing, China.
Y-P SongHenan Cancer Center, Zhengzhou, China.
T LiuWest China Hospital, Sichuan University, Chengdu, China.
K-Y LiuPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
X-J HuangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Nanfang Hospital · CNPeking University · CN307th Hospital of Chinese People’s Liberation Army · CNAir Force General Hospital PLA · CNAnhui Provincial Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNChinese PLA General Hospital · CNFirst Affiliated Hospital of GuangXi Medical University · CNFirst Affiliated Hospital of Soochow University · CNFirst Affiliated Hospital Zhejiang University · CNHenan Cancer Hospital · CNInstitute of Hematology & Blood Diseases Hospital · CNPeking University People's Hospital · CNSecond Military Medical University · CNShanghai Children's Medical Center · CNShanghai First People's Hospital · CNWest China Hospital of Sichuan University · CNWuhan Union Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematopoietic cell transplantation (HCT) activity in China was surveyed to assess its current status. A record number of HCTs (21 884: 16 631 allogeneic (76%) and 5253 autologous (24%)) were reported by 76 centers in China between 1 January 2008 and 30 June 2016. HCT trends included continued growth in transplant activity, a continued rapid increase in haploidentical donors (HID), and slower growth for unrelated donors, matched-related donors (MRD) and cord blood transplantation (CBT). The proportion of HID HCT among allogeneic HCTs increased from 29.6% (313/1062) in 2008 to 48.8% (1939/3975) in 2015, even 51.7% (1157/2237) in the first half of 2016. During this time frame, the proportion of MRD HCTs among allogeneic HCTs decreased from 48.1% (511/1062) to 33.0% (332/3975). The proportion of unrelated donor HCTs among allogeneic HCTs decreased from 20.4 (216/1062) to 13.6% (540/3975). The proportion of CBTs among allogeneic HCTs was increased from 2.1% (22/1062) to 4.2% (184/3975). HCTs have been increasing continuously for all indications except chronic myelogenous leukemia. Severe aplastic anemia is a common HCT indication among non-malignant diseases in China. The number of cases of allogeneic HCT for this disorder has increased annually, from 59 (5.6%) in 2008 to 569 (14.3%) in 2015, even 334 (14.9%) in the first half year in 2016. This survey clearly shows recent trends for HCTs in China.

Indexed as

Anemia, AplasticChinaHematopoietic Stem Cell TransplantationHumansSurveys and QuestionnairesTissue Donors

Identifiers

PMID28436973
OpenAlexW2608397654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.