ArticleDevelopmental cognitive neuroscience2017
Ventral striatal activity links adversity and reward processing in children.
Article in Developmental cognitive neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effects of childhood adversity: Two specific neural patterns.Neuroscience and biobehavioral reviews · 2025Pooled it
- Early life adversity disrupts adult social reward motivation.bioRxiv : the preprint server for biology · 2026Article
- Early parenting is associated with the development of neural reward responsiveness from childhood through adolescence.Communications psychology · 2026Article
- Striatal Prediction Error Tracking Moderates the Influence of Social Exposure on Adolescent Substance Use Curiosity.Human brain mapping · 2026Article
- Adolescent stress exposure induces persistent, sex-specific cognitive deficits.Neurobiology of learning and memory · 2025Article
- Article
- The neurobiological effects of childhood maltreatment on brain structure, function, and attachment.European archives of psychiatry and clinical neuroscience · 2025Review
- Adverse childhood experiences and internalizing symptoms: the moderating role of neural responses to threat.Neurobiology of stress · 2025Article
- The mind, brain, and body study: A protocol for examining the effects of the gut-brain-immune axis on internalizing symptoms in youth exposed to caregiving-related early adversity.Brain, behavior, & immunity - health · 2024Article
- Severe sexual abuse in childhood and altered neurophysiological response to reward in female adults.Child abuse & neglect · 2024Article
- Exposure to community violence as a mechanism linking neighborhood socioeconomic disadvantage and neural responses to reward.Social cognitive and affective neuroscience · 2024Article
- Effects of Maternal Separation on Effort-based Responding for Sucrose Are Associated with c-Fos Expression in the Nucleus Accumbens Core.Neuroscience · 2024Article
- Structure-function coupling within the reward network in preschool children predicts executive functioning in later childhood.Developmental cognitive neuroscience · 2022Article
- Prefrontal modulation of frustration-related physiology in preschool children ranging from low to severe irritability.Developmental cognitive neuroscience · 2022Article
- Limitations of the protective measure theory in explaining the role of childhood sexual abuse in eating disorders, addictions, and obesity: an updated model with emphasis on biological embedding.Eating and weight disorders : EWD · 2022Review
- Impact of Early Life Stress on Reward Circuit Function and Regulation.Frontiers in psychiatry · 2021Review
- The Developmental Origins of Opioid Use Disorder and Its Comorbidities.Frontiers in human neuroscience · 2021Review
- Early life stress and development: potential mechanisms for adverse outcomes.Journal of neurodevelopmental disorders · 2020Review
- A role for adaptive developmental plasticity in learning and decision making.Current opinion in behavioral sciences · 2020Article
- Developmental trajectories to reduced activation of positive valence systems: A review of biological and environmental contributions.Developmental cognitive neuroscience · 2020Review
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adversity impacts many aspects of psychological and physical development including reward-based learning and decision-making. Mechanisms relating adversity and reward processing in children, however, remain unclear. Here, we show that adversity is associated with potentiated learning from positive outcomes and impulsive decision-making, but unrelated to learning from negative outcomes. We then show via functional magnetic resonance imaging that the link between adversity and reward processing is partially mediated by differences in ventral striatal response to rewards. The findings suggest that early-life adversity is associated with alterations in the brain's sensitivity to rewards accounting, in part, for the link between adversity and altered reward processing in children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.