Evidence map›Paper›PMID 28436820›Full record

ArticleeLife2017

sRNA-mediated activation of gene expression by inhibition of 5'-3' exonucleolytic mRNA degradation.

Sylvain Durand, Frédérique Braun, Anne-Catherine Helfer, Pascale Romby, Ciarán Condon

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 51 citations in OpenAlex.

  1. A small RNA fromVirulence · 2025
    Article
  2. Article
  3. Regulatory RNAs inSynthetic and systems biotechnology · 2024
    Review
  4. Factors impacting the regulation ofMicrobiology spectrum · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Microorganisms · 2021
    Review
  9. Article
  10. Article
  11. Prevalence of small base-pairing RNAs derived from diverse genomic loci.Biochimica et biophysica acta. Gene regulatory mechanisms · 2020
    Review
  12. Article
  13. Article
  14. Intermolecular Communication inFrontiers in molecular biosciences · 2020
    Review
  15. Review
  16. Article
  17. Noncoding RNA.Microbiology spectrum · 2019
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sylvain DurandUMR8261 CNRS, Université Paris Diderot (Sorbonne Paris Cité), Institut de Biologie Physico-Chimique, Paris, France.ORCID 0000-0003-3509-6463
Frédérique BraunUMR8261 CNRS, Université Paris Diderot (Sorbonne Paris Cité), Institut de Biologie Physico-Chimique, Paris, France.
Anne-Catherine HelferUniversité de Strasbourg, CNRS, Architecture et Réactivité de l'ARN, Strasbourg, France.
Pascale RombyUMR8261 CNRS, Université Paris Diderot (Sorbonne Paris Cité), Institut de Biologie Physico-Chimique, Paris, France.
Ciarán CondonUMR8261 CNRS, Université Paris Diderot (Sorbonne Paris Cité), Institut de Biologie Physico-Chimique, Paris, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transcriptional control by small regulatory RNA (sRNA) is critical for rapid adaptive processes. sRNAs can directly modulate mRNA degradation in Proteobacteria without interfering with translation. However, Firmicutes have a fundamentally different set of ribonucleases for mRNA degradation and whether sRNAs can regulate the activity of these enzymes is an open question. We show that

Indexed as

Transcriptional ActivationBacillus subtilisGene Expression Regulation, BacterialRibonucleasesRNA, MessengerRNA, Small UntranslatedRNA StabilityStaphylococcus aureusRibonucleasesRNA, MessengerRNA, Small UntranslatedB. subtilischromosomesgenesinfectious diseasemalatemicrobiologyRexribonucleasesRNA degradationRoxSsRNA

Identifiers

PMID28436820
PMCPMC5419742
OpenAlexW2609794067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.