Evidence map›Paper›PMID 28436536›Full record

ArticleThe Journal of physiology2017

Early vertebrate origin and diversification of small transmembrane regulators of cellular ion transport.

Sergej Pirkmajer, Henriette Kirchner, Leonidas S Lundell, Pavel V Zelenin, Juleen R Zierath, Kira S Makarova, Yuri I Wolf, Alexander V Chibalin

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. FXYD proteins and sodium pump regulatory mechanisms.The Journal of general physiology · 2021
    Review
  3. The role of AMPK in regulation of NaJournal of muscle research and cell motility · 2021
    Review
  4. The hidden world of membrane microproteins.Experimental cell research · 2020
    Review
  5. Article
  6. FXYD8, a Novel Regulator of Renal NaFrontiers in physiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Sergej PirkmajerInstitute of Pathophysiology, Faculty of Medicine, University of Ljubljana, SI-1000, Ljubljana, Slovenia.ORCID 0000-0003-1459-6936
Henriette KirchnerDepartment of Physiology and Pharmacology, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
Leonidas S LundellDepartment of Physiology and Pharmacology, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
Pavel V ZeleninDepartment of Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
Juleen R ZierathDepartment of Physiology and Pharmacology, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
Kira S MakarovaNational Center for Biotechnology Information, NLM, National Institutes of Health, Bethesda, MD, 20894, USA.
Yuri I WolfNational Center for Biotechnology Information, NLM, National Institutes of Health, Bethesda, MD, 20894, USA.
Alexander V ChibalinDepartment of Molecular Medicine and Surgery, Karolinska Institutet, SE-171 77, Stockholm, Sweden.ORCID 0000-0002-6339-6271
Karolinska Institutet · SENational Institutes of Health · USUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key pointsSmall transmembrane proteins such as FXYDs, which interact with Na ABSTRACT: Small transmembrane proteins are important for regulation of cellular ion transport. The most prominent among these are members of the FXYD family (FXYD1-12), which regulate Na

Indexed as

AnimalsBiological EvolutionIon TransportLampreysMembrane ProteinsMembrane ProteinsFXYD proteinsmicropeptidesNa+−K+−ATPasephospholemmanprotein phosphorylationSERCAvertebrate evolution

Identifiers

PMID28436536
PMCPMC5509871
OpenAlexW2607701974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.