ArticleNature communications2017
Volumetric chemical imaging by stimulated Raman projection microscopy and tomography.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Label-Free Imaging of Matrix Mineralization in Alginate-Encapsulated Bone Spheroids Using Coherent Raman Scattering Microscopy.Chemical & biomedical imaging · 2026Article
- Hyperspectral coherent anti-Stokes Raman scattering volumetric projection microscopy for assessing drug-cell interaction.Biomedical optics express · 2026Article
- Advanced vibrational microscopes for life science.Nature methods · 2025Review
- Photon-counting Raman spectroscopy at a MHz spectral rate for biochemical imaging of an entire organism.Nature communications · 2025Article
- Advanced Imaging Integration: Multi-Modal Raman Light Sheet Microscopy Combined with Zero-Shot Learning for Denoising and Super-Resolution.Sensors (Basel, Switzerland) · 2024Article
- Label-free 3D molecular imaging of living tissues using Raman spectral projection tomography.Nature communications · 2024Article
- Ultra-low-cost and high-fidelity NIR-II confocal laser scanning microscope with Bessel beam excitation and SiPM detection.Biomedical optics express · 2024Article
- Time-of-flight resolved stimulated Raman scattering microscopy using counter-propagating ultraslow Bessel light bullets generation.Light, science & applications · 2024Article
- Harnessing the power of optical microscopy for visualization and analysis of histopathological images.Biomedical optics express · 2023Review
- 3D Chemical Imaging by Fluorescence-detected Mid-Infrared Photothermal Fourier Light Field Microscopy.Chemical & biomedical imaging · 2023Article
- Label-free structural and functional volumetric imaging by dual-modality optical-Raman projection tomography.Science advances · 2023Article
- Light-field microscopy with temporal focusing multiphoton illumination for scanless volumetric bioimaging.Biomedical optics express · 2022Article
- Tilt-angle stimulated Raman projection tomography.Optics express · 2022Article
- High-precision neural stimulation through optoacoustic emitters.Neurophotonics · 2022Article
- Two-stage deep learning network-based few-view image reconstruction for parallel-beam projection tomography.Quantitative imaging in medicine and surgery · 2022Article
- Quantitative chemical sensing of drugs in scattering media with Bessel beam Raman spectroscopy.Biomedical optics express · 2022Article
- Depth-of-field extension in optical imaging for rapid crystal screening.Acta crystallographica. Section D, Structural biology · 2021Article
- Recurrent neural network-based volumetric fluorescence microscopy.Light, science & applications · 2021Article
- Plasmon-enhanced coherent anti-stokes Raman scattering vs plasmon-enhanced stimulated Raman scattering: Comparison of line shape and enhancement factor.The Journal of chemical physics · 2021Article
- Editorial: Imaging Technology in Oncology Pharmacological Research.Frontiers in pharmacology · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Volumetric imaging allows global understanding of three-dimensional (3D) complex systems. Light-sheet fluorescence microscopy and optical projection tomography have been reported to image 3D volumes with high resolutions and at high speeds. Such methods, however, usually rely on fluorescent labels for chemical targeting, which could perturb the biological functionality in living systems. We demonstrate Bessel-beam-based stimulated Raman projection (SRP) microscopy and tomography for label-free volumetric chemical imaging. Our SRP microscope enables fast quantitation of chemicals in a 3D volume through a two-dimensional lateral scan. Furthermore, combining SRP and sample rotation, we demonstrate the SRP tomography that can reconstruct the 3D distribution of chemical compositions with optical spatial resolution at a higher speed than the Gaussian-beam-based stimulated Raman scattering sectioning imaging can. We explore the potential of our SRP technology by mapping polymer particles in 3D volumes and lipid droplets in adipose cells.
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Registered trials
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