Evidence map›Paper›PMID 28436443›Full record

ArticleScientific reports2017

Curcumol allosterically modulates GABA(A) receptors in a manner distinct from benzodiazepines.

Yan-Mei Liu, Hui-Ran Fan, Jing Ding, Chen Huang, Shining Deng, Tailin Zhu, Tian-Le Xu, Wei-Hong Ge, Wei-Guang Li, Fei Li

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Extract ofFrontiers in cellular neuroscience · 2022
    Article
  9. Article
  10. Article
  11. The Aging GABAergic System and Its Nutritional Support.Journal of nutrition and metabolism · 2021
    Review
  12. Article
  13. Review
  14. Curcumol: From Plant Roots to Cancer Roots.International journal of biological sciences · 2019
    Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yan-Mei LiuDepartment of Chinese Materia Medica, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Hui-Ran FanDepartment of Chinese Materia Medica, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Jing DingPharmacy Department, Affiliated Hospital of Taishan Medical University, Taishan 271000, China.
Chen HuangCollaborative Innovation Centre for Brain Science, and Department of Anatomy, Histology and Embryology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Shining DengDepartment of Children and Adolescent Health Care, Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Tailin ZhuDepartment of Children and Adolescent Health Care, Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Tian-Le XuCollaborative Innovation Centre for Brain Science, and Department of Anatomy, Histology and Embryology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Wei-Hong GeDepartment of Chinese Materia Medica, College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Wei-Guang LiDepartment of Children and Adolescent Health Care, Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Fei LiDepartment of Children and Adolescent Health Care, Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Shanghai Jiao Tong University · CNZhejiang Chinese Medical University · CNXinHua Hospital · CNAffiliated Hospital of Taishan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibitory A type γ-aminobutyric acid receptors (GABA

Indexed as

Allosteric RegulationAnimalsBenzodiazepinesCA1 Region, HippocampalCells, CulturedDiazepamDrugs, Chinese HerbalFlumazenilGABA Modulatorsgamma-Aminobutyric AcidHEK293 CellsHumansMembrane PotentialsPyramidal CellsReceptors, GABA-ASesquiterpenesBenzodiazepinescurcumolDiazepamDrugs, Chinese HerbalFlumazenilGABA Modulatorsgamma-Aminobutyric AcidReceptors, GABA-ASesquiterpenes

Identifiers

PMID28436443
PMCPMC5402396
OpenAlexW2608866126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.