Evidence map›Paper›PMID 28436410›Full record

ArticleJournal of X-ray science and technology2017

A new approach to develop computer-aided diagnosis scheme of breast mass classification using deep learning technology.

Yuchen Qiu, Shiju Yan, Rohith Reddy Gundreddy, Yunzhi Wang, Samuel Cheng, Hong Liu, Bin Zheng

Abstract read
In one paragraph

Article in Journal of X-ray science and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 105 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yuchen QiuSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA.
Shiju YanUniversity of Shanghai for Sciences and Technology, Shanghai, China.
Rohith Reddy GundreddySchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA.
Yunzhi WangSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA.
Samuel ChengSchool of Electrical and Computer Engineering, University of Oklahoma, Tulsa, OK, USA.
Hong LiuSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA.
Bin ZhengSchool of Electrical and Computer Engineering, University of Oklahoma, Norman, OK, USA.
University of Oklahoma · USUniversity of Shanghai for Science and Technology · CNUniversity of Tulsa · US

Funding

Increasing Cancer Detection Yield Using Breast MRI Screening ModalityR01CA197150 · NCI · UNIVERSITY OF OKLAHOMA · PI HOLLINGSWORTH, ALAN B., LIU, HONG · 2015 to 2019
$2.5M
Mammographic Density and Tissue Asymmetry Based Breast Cancer Risk StratificationR01CA160205 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZHENG, BIN · 2012 to 2015
$895k
NCI NIH HHS R01 CA160205NCI NIH HHS R01 CA197150
6 · The paper itself

Abstract

purposeTo develop and test a deep learning based computer-aided diagnosis (CAD) scheme of mammograms for classifying between malignant and benign masses.

methodsAn image dataset involving 560 regions of interest (ROIs) extracted from digital mammograms was used. After down-sampling each ROI from 512×512 to 64×64 pixel size, we applied an 8 layer deep learning network that involves 3 pairs of convolution-max-pooling layers for automatic feature extraction and a multiple layer perceptron (MLP) classifier for feature categorization to process ROIs. The 3 pairs of convolution layers contain 20, 10, and 5 feature maps, respectively. Each convolution layer is connected with a max-pooling layer to improve the feature robustness. The output of the sixth layer is fully connected with a MLP classifier, which is composed of one hidden layer and one logistic regression layer. The network then generates a classification score to predict the likelihood of ROI depicting a malignant mass. A four-fold cross validation method was applied to train and test this deep learning network.

resultsThe results revealed that this CAD scheme yields an area under the receiver operation characteristic curve (AUC) of 0.696±0.044, 0.802±0.037, 0.836±0.036, and 0.822±0.035 for fold 1 to 4 testing datasets, respectively. The overall AUC of the entire dataset is 0.790±0.019.

conclusionsThis study demonstrates the feasibility of applying a deep learning based CAD scheme to classify between malignant and benign breast masses without a lesion segmentation, image feature computation and selection process.

Indexed as

Machine LearningAlgorithmsBreast NeoplasmsFemaleHumansImage Interpretation, Computer-AssistedMammographyNeural Networks, Computerbreast mass classificationComputer aided diagnosis (CAD)convolution neuron networksdeep learning

Identifiers

PMID28436410
PMCPMC5647205
OpenAlexW2606915180

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.