Trial reportJournal of diabetes science and technology2017
Does Physiological Stress Slow Down Wound Healing in Patients With Diabetes?
Trial report in Journal of diabetes science and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Mobile and Wearable Technology for the Monitoring of Diabetes-Related Parameters: Systematic Review.JMIR mHealth and uHealth · 2021Pooled it
- The Impact of Adjunctive Acupressure on Postoperative Infection and Hospital Stay in Wagner Grade 2-3 Diabetic Foot Ulcers: A Propensity Score-Stratified Cohort Study.International wound journal · 2026Article
- Differential Maternal Physiological Stress Responses During Rooming-In: High Stress in Newborn Sleeping versus Relief in Breastfeeding.International journal of women's health · 2026Article
- Wound management, healing, and early prosthetic rehabilitation: Part 3 - A scoping review of chemical biomarkers.Canadian prosthetics & orthotics journal · 2025Review
- Psychosocial Care for People With Diabetic Neuropathy: Time for Action.Diabetes care · 2024Review
- How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs.Advances in wound care · 2024Review
- Wound management, healing, and early prosthetic rehabilitation: Part 1 - A scoping review of healing and non-healing definitions.Canadian prosthetics & orthotics journal · 2024Review
- Wound management, healing, and early prosthetic rehabilitation: Part 2 - A scoping review of physical biomarkers.Canadian prosthetics & orthotics journal · 2024Review
- Pilot Study for Correlation of Heart Rate Variability and Dopamine Transporter Brain Imaging in Patients with Parkinsonian Syndrome.Sensors (Basel, Switzerland) · 2022Article
- Harnessing Digital Health Technologies to Remotely Manage Diabetic Foot Syndrome: A Narrative Review.Medicina (Kaunas, Lithuania) · 2021Review
- Noninvasive Continuous Monitoring of Vital Signs With Wearables: Fit for Medical Use?Journal of diabetes science and technology · 2021Article
- Wellbuilt for wellbeing: Controlling relative humidity in the workplace matters for our health.Indoor air · 2020Article
- Hemodialysis Impact on Motor Function beyond Aging and Diabetes-Objectively Assessing Gait and Balance by Wearable Technology.Sensors (Basel, Switzerland) · 2018Article
- Health Sensors, Smart Home Devices, and the Internet of Medical Things: An Opportunity for Dramatic Improvement in Care for the Lower Extremity Complications of Diabetes.Journal of diabetes science and technology · 2018Review
- Psychological and Biomechanical Aspects of Patient Adaptation to Diabetic Neuropathy and Foot Ulceration.Current diabetes reports · 2017Review
- Racial/ethnic disparities in chronic wounds: Perspectives on linking upstream factors to health outcomes.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyReview
- Lifestyle Medicine Approach to Wound Management.American journal of lifestyle medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPoor healing is an important contributing factor to amputation among patients with diabetic foot ulcers (DFUs). Physiological stress may slow wound healing and increase susceptibility to infection.
objectivesThe objective was to examine the association between heart rate variability (HRV) as an indicator of physiological stress response and healing speed (Heal DESIGN AND
methodsAmbulatory patients with diabetes with DFUs (n = 25, age: 59.3 ± 8.3 years) were recruited. HRV during pre-wound dressing was measured using a wearable sensor attached to participants' chest. HRVs were quantified in both time and frequency domains to assess physiological stress response and vagal tone (relaxation). Change in wound size between two consecutive visits was used to estimate Heal
resultsHeal
conclusionThis study confirms an association between stress/vagal tone and wound healing in patients with DFUs. In particular, it highlights the importance of vagal tone (relaxation) in expediting wound healing. It also demonstrates the feasibility of assessing physiological stress responses using wearable technology in outpatient clinic during routine clinic visits.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.