ArticleCancer2017
Is prostate cancer different in black men? Answers from 3 natural history models.
Article in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 6 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
84 citing papers in PubMed, 6 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- The association between zinc and prostate cancer development: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Early Detection of Prostate Cancer: AUA/SUO Guideline Part I: Prostate Cancer Screening.The Journal of urology · 2023Guideline
- Does testosterone mediate the relationship between vitamin D and prostate cancer progression? A systematic review and meta-analysis.Cancer causes & control : CCC · 2022Pooled it
- Prostate Cancer: Community Education and Disparities in Diagnosis and Treatment.The oncologist · 2021Pooled it
- Choosing Channels, Sources, and Content for Communicating Prostate Cancer Information to Black Men: A Systematic Review of the Literature.American journal of men's health · 2018Pooled it
- Identifying quality of life indicators to improve outpatient pharmacy services for prostate cancer patients: a comparison between Brazilian and British experiences.International braz j urol : official journal of the Brazilian Society of UrologyPooled it
- Active Surveillance for Prostate Cancer in "Real-World" Setting: Exploring Racial Disparities.Journal of racial and ethnic health disparities · 2026Article
- Using a Community-Embedded Screening and Navigation Framework to Engage High-Risk Men in Prostate Cancer Early Detection: Five Years of the Men's Health Awareness Summit in Oklahoma.Journal of racial and ethnic health disparities · 2026Article
- Racial Differences in Secondary Treatment Pathways and Survival in Localized Prostate Cancer.JAMA network open · 2026Article
- Platelet-Prostate cancer crosstalk driving disparities and therapeutic vulnerabilities.Discover oncology · 2026Review
- Quality of life assessment among ethnically diverse Black prostate cancer survivors: a constructivist grounded theory approach.Journal of cancer survivorship : research and practice · 2025Article
- Age-specific racial disparities in the incidence of fatal prostate cancer: an analytic deconstruction.JNCI cancer spectrum · 2025Article
- Select black men are potential candidates for prostate hemi-ablation based on radical prostatectomy histopathology for intermediate-risk prostate cancer-a multicenter SEARCH cohort study.Prostate cancer and prostatic diseases · 2025Article
- Individual income and race-associated differences in prostate cancer mortality in a statewide registry.JNCI cancer spectrum · 2025Article
- Trends in young-onset cancer incidence: a modeling perspective.Journal of the National Cancer Institute · 2025Article
- Engaging for equity: Lessons from a cross-sector partnership addressing prostate cancer risk in the black community.Research involvement and engagement · 2025Article
- Negative Predictive Value of a Prostate MRI in Black Men: Implications for Biopsy Decision-Making.The Journal of urology · 2025Article
- Exploring prostate-specific antigen (PSA) Testing rates and screening disparities in the all of us dataset.Urologic oncology · 2025Article
- Exploration of social determinants of health and prostate cancer prevalence in the US: a cross-sectional study of NHANES data from 2003 to 2010.Frontiers in public health · 2025Article
- Identification of Factors Affecting the Accrual of Black Males Into Prostate Cancer Clinical Trials in the United States.Urology practice · 2025Article
24 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundBlack men in the United States have substantially higher prostate cancer incidence rates than the general population. The extent to which this incidence disparity is because prostate cancer is more prevalent, more aggressive, and/or more frequently diagnosed in black men is unknown.
methodsThe authors estimated 3 independently developed models of prostate cancer natural history in black men and in the general population using an updated reconstruction of prostate-specific antigen screening, based on the National Health Interview Survey in 2005 and on prostate cancer incidence data from the Surveillance, Epidemiology, and End Results program during 1975 through 2000. By using the estimated models, the natural history of prostate cancer was compared between black men and the general population.
resultsThe models projected that from 30% to 43% (range across models) of black men develop preclinical prostate cancer by age 85 years, a risk that is (relatively) 28% to 56% higher than that in the general population. Among men who had preclinical disease onset, black men had a similar risk of diagnosis (range, 35%-49%) compared with the general population (32%-44%), but their risk of progression to metastatic disease by the time of diagnosis was from 44% to 75% higher than that in the general population.
conclusionsProstate cancer incidence patterns implicate higher incidence of preclinical disease and higher risk of metastatic progression among black men. The findings suggest screening black men earlier than white men and support further research into the benefit-harm tradeoffs of more aggressive screening policies for black men. Cancer 2017;123:2312-2319. © 2017 American Cancer Society.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.