ArticleAlzheimer's & dementia (New York, N. Y.)2017
Preclinical Alzheimer's disease and longitudinal driving decline.
Article in Alzheimer's & dementia (New York, N. Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Sensorimotor function as an early marker of cognitive decline and alzheimer's biomarker burden.GeroScience · 2026Article
- White Matter Hyperintensity Burden and Decline in Driving Performance Among Older Adults.JAMA network open · 2026Article
- Association of Daily Driving Behaviors With Mild Cognitive Impairment in Older Adults Followed Over 10 Years.Neurology · 2025Observational
- Slowed Driving Reaction Time in Preclinical Alzheimer's Disease.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- A combined naturalistic driving, clinical, and neurobehavioral data set for investigating aging and dementia.Scientific data · 2025Article
- Integrating Machine Learning and Environmental and Genetic Risk Factors for the Early Detection of Preclinical Alzheimer's Disease.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Enhancing road safety: In-vehicle sensor analysis of cognitive impairment in older drivers.Multimedia tools and applications · 2025Article
- Predicting Driving Cessation Among Cognitively Normal Older Drivers: The Role of Alzheimer Disease Biomarkers and Clinical Assessments.Neurology · 2024Observational
- Impact of cognitive impairment on driving behaviour and route choices of older drivers: a real-world driving study.Scientific reports · 2024Article
- Digital Neuropsychology beyond Computerized Cognitive Assessment: Applications of Novel Digital Technologies.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Review
- Falls and Alzheimer Disease.Advances in geriatric medicine and research · 2024Article
- Differential Impacts of Road Diets on Driving Behavior among Older Adults with and without Preclinical Alzheimer's Pathology.Transportation research. Part F, Traffic psychology and behaviour · 2023Article
- Medication and Road Test Performance Among Cognitively Healthy Older Adults.JAMA network open · 2023Article
- Adverse driving behaviors increase over time as a function of preclinical Alzheimer's disease biomarkers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Matching science to reality: how to deploy a participant-driven digital brain health platform.Frontiers in dementia · 2023Article
- Associations Between Plasma, Imaging, and Cerebrospinal Fluid Biomarkers with Driving Behavior and Cognitive Tests: Implications for Biomarker Usefulness.Journal of Alzheimer's disease reports · 2023Article
- Article
- Everyday Driving and Plasma Biomarkers in Alzheimer's Disease: Leveraging Artificial Intelligence to Expand Our Diagnostic Toolkit.Journal of Alzheimer's disease : JAD · 2023Article
- Driving assessment in preclinical Alzheimer's disease: progress to date and the path forward.Alzheimer's research & therapy · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
Abstract
introductionLinks between preclinical AD and driving difficulty onset would support the use of driving performance as an outcome in primary and secondary prevention trials among older adults (OAs). We examined whether AD biomarkers predicted the onset of driving difficulties among OAs.
methods104 OAs (65+ years) with normal cognition took part in biomarker measurements, a road test, clinical and psychometric batteries and self-reported their driving habits.
resultsHigher values of CSF tau/Aβ DISCUSSION: Preclinical AD predicted time to receiving a Marginal or Fail rating on an on-road driving test. Driving performance shows promise as a functional outcome in AD prevention trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.