Evidence map›Paper›PMID 28435838›Full record

ArticleMicrobial cell (Graz, Austria)2017

Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload.

Anup Arunrao Deshpande, Muskan Bhatia, Sunil Laxman, Anand Kumar Bachhawat

Open access · goldAbstract read
In one paragraph

Article in Microbial cell (Graz, Austria), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Avirulent phenotype promotesEmerging microbes & infections · 2023
    Article
  5. Review
  6. Article
  7. Review
  8. Arsenic exposure increased expression of HOTAIR and LincRNA-p21 in vivo and vitro.Environmental science and pollution research international · 2021
    Article
  9. Simultaneous Interpenetrating Polymer Network of Collagen and Hyaluronic Acid as anChemistry of materials : a publication of the American Chemical Society · 2020
    Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anup Arunrao DeshpandeDepartment of Biological Sciences, Indian Institute of Science Education and Research (IISER Mohali), S.A.S. Nagar, Punjab 140306, India.
Muskan BhatiaDepartment of Biological Sciences, Indian Institute of Science Education and Research (IISER Mohali), S.A.S. Nagar, Punjab 140306, India.
Sunil LaxmanInstitute for Stem Cell Biology and Regenerative Medicine (inStem), NCBS campus, Bangalore 560065, India.
Anand Kumar BachhawatDepartment of Biological Sciences, Indian Institute of Science Education and Research (IISER Mohali), S.A.S. Nagar, Punjab 140306, India.
Indian Institute of Science Education and Research Mohali · INInstitute for Stem Cell Biology and Regenerative Medicine · IN

Funding

DBT-Wellcome Trust India Alliance IA/I/14/2/501523Wellcome Trust
6 · The paper itself

Abstract

Cysteine is an essential requirement in living organisms. However, due to its reactive thiol side chain, elevated levels of intracellular cysteine can be toxic and therefore need to be rapidly eliminated from the cellular milieu. In mammals and many other organisms, excess cysteine is believed to be primarily eliminated by the cysteine dioxygenase dependent oxidative degradation of cysteine, followed by the removal of the oxidative products. However, other mechanisms of tackling excess cysteine are also likely to exist, but have not thus far been explored. In this study, we use

Indexed as

biosynthesiscysteinepolyamineSaccharomyces cerevisiaethioltoxicity

Identifiers

PMID28435838
PMCPMC5376351
OpenAlexW2602874282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.