ArticlePilot and feasibility studies2015
Feasibility of titrating PEEP to minimum elastance for mechanically ventilated patients.
Article in Pilot and feasibility studies, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 56 citations in OpenAlex.
- A single compartment model to describe lung functionality: A comprehensive study.Physiological reports · 2026Review
- Monitoring of invasive assisted mechanical ventilation: a good clinical practice document by the Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care (SIAARTI).Journal of anesthesia, analgesia and critical care · 2025Review
- Pulmonary function testing dataset of pressure and flow, dynamic circumference, heart rate, and aeration monitoring.Data in brief · 2024Article
- Automated evaluation of typical patient-ventilator asynchronies based on lung hysteretic responses.Biomedical engineering online · 2023Article
- Quantifying neonatal patient effort using non-invasive model-based methods.Medical & biological engineering & computing · 2022Article
- Stochastic integrated model-based protocol for volume-controlled ventilation setting.Biomedical engineering online · 2022Article
- Model-based patient matching for in-parallel pressure-controlled ventilation.Biomedical engineering online · 2022Article
- Assessing the Asynchrony Event Based on the Ventilation Mode for Mechanically Ventilated Patients in ICU.Bioengineering (Basel, Switzerland) · 2021Article
- Stochastic Modelling of Respiratory System Elastance for Mechanically Ventilated Respiratory Failure Patients.Annals of biomedical engineering · 2021Observational
- Model-based PEEP titration versus standard practice in mechanical ventilation: a randomised controlled trial.Trials · 2020Article
- Optimising mechanical ventilation through model-based methods and automation.Annual reviews in control · 2019Review
- Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to validation them.Biomedical engineering online · 2018Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSelecting positive end-expiratory pressure (PEEP) during mechanical ventilation is important, as it can influence disease progression and outcome of acute respiratory distress syndrome (ARDS) patients. However, there are no well-established methods for optimizing PEEP selection due to the heterogeneity of ARDS. This research investigates the viability of titrating PEEP to minimum elastance for mechanically ventilated ARDS patients.
methodsTen mechanically ventilated ARDS patients from the Christchurch Hospital Intensive Care Unit were included in this study. Each patient underwent a stepwise PEEP recruitment manoeuvre. Airway pressure and flow data were recorded using a pneumotachometer. Patient-specific respiratory elastance (
resultsMedian
conclusionsMonitoring patient-specific
trial registrationAustralian New Zealand Clinical Trials Registry: ACTRN12611001179921.
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