ArticleThe Journal of clinical investigation1988
Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.
Article in The Journal of clinical investigation, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
113 citing papers in PubMed, 482 citations in OpenAlex.
- Differential responses to thrombospondin-1 and PDGF-BB in smooth muscle cells from atherosclerotic coronary arteries and internal thoracic arteries.Scientific reports · 2024Article
- Tyrosine kinases: multifaceted receptors at the intersection of several neurodegenerative disease-associated processes.Frontiers in dementia · 2024Review
- Mechanosensory entities and functionality of endothelial cells.Frontiers in cell and developmental biology · 2024Review
- Microvascular smooth muscle cells exhibit divergent phenotypic switching responses to platelet-derived growth factor and insulin-like growth factor 1.Microvascular research · 2024Article
- Pathophysiology of Atherosclerosis.International journal of molecular sciences · 2022Review
- YAP1/TEAD1 upregulate platelet-derived growth factor receptor beta to promote vascular smooth muscle cell proliferation and neointima formation.Journal of molecular and cellular cardiology · 2021Article
- Screening key genes for abdominal aortic aneurysm based on gene expression omnibus dataset.BMC cardiovascular disorders · 2018Article
- Platelet-derived miR-92a downregulates cysteine protease inhibitor cystatin C in type II diabetic lower limb ischemia.Experimental and therapeutic medicine · 2015Article
- Shear stress-initiated signaling and its regulation of endothelial function.Arteriosclerosis, thrombosis, and vascular biology · 2014Review
- Quinazoline derivatives: synthesis and bioactivities.Chemistry Central journal · 2013Article
- Article
- The importance of velocity acceleration to flow-mediated dilation.International journal of vascular medicine · 2012Article
- Platonin inhibited PDGF-BB-induced proliferation of rat vascular smooth muscle cells via JNK1/2-dependent signaling.Acta pharmacologica Sinica · 2011Article
- Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives.Physiological reviews · 2011Review
- Neointimal hyperplasia and vasoreactivity are controlled by genetic elements on rat chromosome 3.Hypertension (Dallas, Tex. : 1979) · 2010Article
- Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle.American journal of physiology. Heart and circulatory physiology · 2009Article
- C-reactive protein and vein graft disease: evidence for a direct effect on smooth muscle cell phenotype via modulation of PDGF receptor-beta.American journal of physiology. Heart and circulatory physiology · 2008Article
- Chronic insulin treatment amplifies PDGF-induced motility in differentiated aortic smooth muscle cells by suppressing the expression and function of PTP1B.American journal of physiology. Heart and circulatory physiology · 2008Article
- Role of smooth muscle cells in the initiation and early progression of atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2008Review
- The role of PDGF in radiation oncology.Radiation oncology (London, England) · 2007Review
53 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Platelet-derived growth factor (PDGF) mRNA, and mRNA for its receptor, have been localized to specific cell types within the human atherosclerotic plaque, using in situ hybridization. The predominant cell types found to express PDGF A and B chain mRNA are mesenchymal-appearing intimal cells and endothelial cells, respectively, with little or no expression detected in macrophages. The distribution of PDGF receptor mRNA containing cells was also examined and found to be localized predominantly in the plaque intima.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.