ArticleACS medicinal chemistry letters2017
The Ecstasy and Agony of Assay Interference Compounds.
Article in ACS medicinal chemistry letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Review
- Preclinical Studies and Drug Combination of Low-Cost Molecules for Chagas Disease.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Dual Targeting of MDM4 and FTH1 by MMRi71 for Induced Protein Degradation and p53-Independent Apoptosis in Leukemia Cells.Molecules (Basel, Switzerland) · 2022Article
- Covalent sortase A inhibitor ML346 preventsRSC medicinal chemistry · 2022Article
- Inhibitors of HIV-1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation.ACS infectious diseases · 2022Article
- 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis.Beilstein journal of organic chemistry · 2022Review
- Article
- Article
- Novel Immune Modulators EnhancemSphere · 2021Article
- Curcumin-1,2,3-Triazole Conjugation for Targeting the Cancer Apoptosis Machinery.Molecules (Basel, Switzerland) · 2020Article
- Quantifying the Interactions between Biomolecules: Guidelines for Assay Design and Data Analysis.ACS infectious diseases · 2019Article
- DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors.ACS medicinal chemistry letters · 2019Article
- Exploration of icariin analog structure space reveals key features driving potent inhibition of human phosphodiesterase-5.PloS one · 2019Article
- Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017-Utility and Limitations.ACS chemical biology · 2018Review
- Chemoinformatic Database Building and in Silico Hit-Identification of Potential Multi-Targeting Bioactive Compounds Extracted from Mushroom Species.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.