Evidence map›Paper›PMID 28435467›Full record

ReviewTheranostics2017

Ultrasound Elastography: Review of Techniques and Clinical Applications.

Rosa M S Sigrist, Joy Liau, Ahmed El Kaffas, Maria Cristina Chammas, Juergen K Willmann

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 816 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
816citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04574531 unknown statusnot on this mapstarted 2021, after this paper: background citation

Comparative Study of US Elastography and Color Doppler US in Differentiating Breast Masses in Correlation to Histopathology

TypeobservationalSponsorAssiut UniversityRan2021 to 2022Enrolled50ConditionsBreast Lump (Malignant)
NCT05776199 nacompletednot on this mapstarted 2022, after this paper: background citation

Sonoelastography, Tensiomyography and Mechanosensitivity Between Latent, Active and Control Trigger Points in Myofascial Trigger Points of the Levator Scapulae Muscle.

TypeinterventionalSponsorUniversidad Católica de ÁvilaRan2022 to 2022Enrolled80ConditionsMyofascial Pain SyndromeArmsSonoelastography, tensiomyography and mechanosensitivity
3 · Its place in the literature

Who cites it

816 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Placental Stiffness Measured by Sonoelastography in Fetal Growth Restriction: A Systematic Review and Meta-Analysis.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Pooled it
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  9. Ultrasonic elastography-guided pleural biopsyThe European respiratory journal · 2025
    Trial
  10. Quantitative Multi-Parameter MRI Evaluation of Hashimoto's Thyroiditis Changes After Dietary Interventions.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Trial
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  20. Observational

756 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rosa M S SigristDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, School of Medicine, Stanford, CA, USA.
Joy LiauDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, School of Medicine, Stanford, CA, USA.
Ahmed El KaffasDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, School of Medicine, Stanford, CA, USA.
Maria Cristina ChammasDepartment of Ultrasound, Institute of Radiology, Hospital das Clínicas, Medical School of University of São Paulo.
Juergen K WillmannDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, School of Medicine, Stanford, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elastography-based imaging techniques have received substantial attention in recent years for non-invasive assessment of tissue mechanical properties. These techniques take advantage of changed soft tissue elasticity in various pathologies to yield qualitative and quantitative information that can be used for diagnostic purposes. Measurements are acquired in specialized imaging modes that can detect tissue stiffness in response to an applied mechanical force (compression or shear wave). Ultrasound-based methods are of particular interest due to its many inherent advantages, such as wide availability including at the bedside and relatively low cost. Several ultrasound elastography techniques using different excitation methods have been developed. In general, these can be classified into strain imaging methods that use internal or external compression stimuli, and shear wave imaging that use ultrasound-generated traveling shear wave stimuli. While ultrasound elastography has shown promising results for non-invasive assessment of liver fibrosis, new applications in breast, thyroid, prostate, kidney and lymph node imaging are emerging. Here, we review the basic principles, foundation physics, and limitations of ultrasound elastography and summarize its current clinical use and ongoing developments in various clinical applications.

Indexed as

Elasticity Imaging TechniquesHumansUltrasonographyBreastElastographyKidneyLiverLymph nodes.ProstateShear Wave ImagingStrain ImagingThyroidUltrasound

Identifiers

PMID28435467
PMCPMC5399595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.