Evidence map›Paper›PMID 28435466›Full record

ArticleTheranostics2017

Design of Tumor Acidity-Responsive Sheddable Nanoparticles for Fluorescence/Magnetic Resonance Imaging-Guided Photodynamic Therapy.

Feng Fan, Yue Yu, Fei Zhong, Meng Gao, Tianmeng Sun, Jiaxin Liu, Huimao Zhang, Haisheng Qian, Wei Tao, Xianzhu Yang

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Functional Polymer Nanocarriers for Photodynamic Therapy.Pharmaceuticals (Basel, Switzerland) · 2018
    Review
  8. Theranostics and metabolotheranostics for precision medicine in oncology.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2018
    Review
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Feng FanSchool of Biological and Medical Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Yue YuDivision of Gastroenterology, Affiliated Provincial Hospital, Anhui Medical University, Anhui 230001, China.
Fei ZhongDepartment of Oncolog, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Meng GaoDivision of Gastroenterology, Affiliated Provincial Hospital, Anhui Medical University, Anhui 230001, China.
Tianmeng SunThe First Hospital and Institute of Immunology, Jilin University, Changchun 130061, P. R. China.
Jiaxin LiuDepartment of Radiology, The First Hospital of JiLin University, Changchun, 130061, P. R. China.
Huimao ZhangDepartment of Radiology, The First Hospital of JiLin University, Changchun, 130061, P. R. China.
Haisheng QianSchool of Biological and Medical Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Wei TaoSchool of Biological and Medical Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Xianzhu YangSchool of Biological and Medical Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.
Hefei University of Technology · CNAnhui Medical University · CNAnhui Provincial Hospital · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging-guided cancer therapy, which integrates diagnostic and therapeutic functionalities into a single system, holds great promise to enhance the accuracy of diagnosis and improve the efficacy of therapy. Specifically, for photodynamic therapy (PDT), it is highly desirable to precisely focus laser light onto the tumor areas to generate reactive oxygen species (ROS) that are cytotoxic tumor cells and avoid light-associated side effects. Herein, a distinct three-layer nanostructured particle with tumor acidity-responsiveness (S-NP) that encapsulates the photosensitizer chlorin e6 (Ce6) and chelates Gd

Indexed as

Magnetic Resonance ImagingOptical ImagingAcidsAntineoplastic AgentsCell Line, TumorChlorophyllidesGadoliniumHumansHydrogen-Ion ConcentrationNanoparticlesNeoplasmsPhotochemotherapyPorphyrinsAcidsAntineoplastic AgentsChlorophyllidesGadoliniumphytochlorinPorphyrinsmagnetic resonance imagingphotodynamic therapysheddable nanoparticlestumor acidity-responsive

Identifiers

PMID28435466
PMCPMC5399594
OpenAlexW2596568395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.