ArticleGastroenterology & hepatology2014
Insight Into the Relationship Between Gastroesophageal Reflux Disease and Asthma.
Article in Gastroenterology & hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Pharmacological and surgical interventions for the treatment of gastro-oesophageal reflux in adults and children with asthma.The Cochrane database of systematic reviews · 2021Pooled it
- Inhaled anti-asthmatic therapy and tooth wear in children and adolescents: a case-control study.Scientific reports · 2025Article
- Review
- High Prevalence of Uncontrolled Asthma and Its Association With Obesity and GERD-Related Symptoms in Syria: A Multicenter Cross-Sectional Study.Health science reports · 2025Article
- Risk factors for asthma-related hospital and intensive care admissions in children, adolescents and adults: a cohort study using primary and secondary care data.BMJ open respiratory research · 2024Article
- Packaging and Delivery of Asthma Therapeutics.Pharmaceutics · 2021Review
- Allergic rhinitis, asthma and laryngopharyngeal reflux disease: a cross-sectional study on their reciprocal relations.Scientific reports · 2021Observational
- Article
- Upper digestive tract abnormalities in dogs with chronic idiopathic lymphoplasmacytic rhinitis.Journal of veterinary internal medicine · 2020Article
- Allergic rhinitis is a risk factor of gastro-esophageal reflux disease regardless of the presence of asthma.Scientific reports · 2019Article
- Indian consensus on gastroesophageal reflux disease in adults: A position statement of the Indian Society of Gastroenterology.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019Article
- Alternative Treatments for Minor GI Ailments.Innovations in pharmacy · 2019Review
- Lung function parameters in patients with gastroesophageal reflux without respiratory symptoms: a case-control study.Gastroenterology and hepatology from bed to bench · 2019Article
- Demographic and clinical patterns of severe asthma in the Middle East.Annals of thoracic medicineArticle
- Clinical features and associated factors with severe asthma in Salvador, Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastroesophageal reflux disease (GERD) is a common condition that presents with symptoms of heartburn and regurgitation. Asthma is an equally common medical condition that often coexists with GERD. The clinical scenario of difficult-to-treat asthma in the setting of concomitant GERD leads to the possibility of GERD-induced asthma. However, asthma may also induce GERD, so confusion has developed about the role of GERD in patients with moderate to severe asthma. Acid-suppressive therapy may be initiated in patients with asthma, but controlled studies have recently questioned the role of such therapy and, thus, have caused further confusion in this field. Recent advancements in the field of esophageal physiologic testing in GERD have introduced the concept of impedance-pH monitoring, which suggests a possible role of nonacid reflux in those who continue to be symptomatic despite acid-suppressive therapy. However, recent data caution about the role of surgical fundoplication based solely on the results of impedance monitoring. This article reviews current knowledge in the fields of GERD and asthma and suggests a possible treatment option for this group of patients.
Indexed as
Identifiers
28435409PMC5395714W2564350167What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.