Evidence map›Paper›PMID 28435407›Full record

ArticleGastroenterology & hepatology2014

Hepatitis C Virus Treatment in HIV-Coinfected Patients: No Longer Different From Monoinfection Treatment.

Bevin Hearn, David Delbello, Joseph Lawler, Michel Ng, Alyson Harty, Douglas T Dieterich

Abstract read
In one paragraph

Article in Gastroenterology & hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bevin HearnDr Hearn and Dr Delbello are fellows in the Division of Infectious Diseases; Dr Lawler is a fellow in the Division of Liver Diseases; Mr Ng is a nurse practitioner in the Division of Infectious Diseases and the Division of Liver Diseases; Ms Harty is a nurse in the Division of Liver Diseases; and Dr Dieterich is a professor in the Division of Infectious Diseases and the Division of Liver Diseases at the Icahn School of Medicine at Mount Sinai in New York, New York.
David DelbelloDr Hearn and Dr Delbello are fellows in the Division of Infectious Diseases; Dr Lawler is a fellow in the Division of Liver Diseases; Mr Ng is a nurse practitioner in the Division of Infectious Diseases and the Division of Liver Diseases; Ms Harty is a nurse in the Division of Liver Diseases; and Dr Dieterich is a professor in the Division of Infectious Diseases and the Division of Liver Diseases at the Icahn School of Medicine at Mount Sinai in New York, New York.
Joseph LawlerDr Hearn and Dr Delbello are fellows in the Division of Infectious Diseases; Dr Lawler is a fellow in the Division of Liver Diseases; Mr Ng is a nurse practitioner in the Division of Infectious Diseases and the Division of Liver Diseases; Ms Harty is a nurse in the Division of Liver Diseases; and Dr Dieterich is a professor in the Division of Infectious Diseases and the Division of Liver Diseases at the Icahn School of Medicine at Mount Sinai in New York, New York.
Michel NgDr Hearn and Dr Delbello are fellows in the Division of Infectious Diseases; Dr Lawler is a fellow in the Division of Liver Diseases; Mr Ng is a nurse practitioner in the Division of Infectious Diseases and the Division of Liver Diseases; Ms Harty is a nurse in the Division of Liver Diseases; and Dr Dieterich is a professor in the Division of Infectious Diseases and the Division of Liver Diseases at the Icahn School of Medicine at Mount Sinai in New York, New York.
Alyson HartyDr Hearn and Dr Delbello are fellows in the Division of Infectious Diseases; Dr Lawler is a fellow in the Division of Liver Diseases; Mr Ng is a nurse practitioner in the Division of Infectious Diseases and the Division of Liver Diseases; Ms Harty is a nurse in the Division of Liver Diseases; and Dr Dieterich is a professor in the Division of Infectious Diseases and the Division of Liver Diseases at the Icahn School of Medicine at Mount Sinai in New York, New York.
Douglas T DieterichDr Hearn and Dr Delbello are fellows in the Division of Infectious Diseases; Dr Lawler is a fellow in the Division of Liver Diseases; Mr Ng is a nurse practitioner in the Division of Infectious Diseases and the Division of Liver Diseases; Ms Harty is a nurse in the Division of Liver Diseases; and Dr Dieterich is a professor in the Division of Infectious Diseases and the Division of Liver Diseases at the Icahn School of Medicine at Mount Sinai in New York, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Between 15% and 30% of patients infected with HIV in the United States and Europe are coinfected with hepatitis C virus (HCV), and rates of acute HCV infection have been increasing in some populations of HIV-positive patients. Liver disease is now a leading cause of death in HIV-infected patients. Patients with HIV/HCV coinfection have lower rates of spontaneous acute HCV clearance, poorer response to treatment of chronic HCV in the pre-direct-acting antiviral era, more rapid progression to cirrhosis, and increased risk of hepatocellular carcinoma. This article will summarize data on management of HIV/HCV coinfection, discuss the epidemic of acute HCV infection in HIV-infected patients, and examine the many new HCV treatment regimens on the horizon with data on coinfected patients.

Indexed as

acute hepatitis CHepatitis C virusHIV/HCV coinfectionHIV/HCV management

Identifiers

PMID28435407
PMCPMC5395712

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.