Evidence map›Paper›PMID 28435394›Full record

ReviewContemporary oncology (Poznan, Poland)2017

The role of mast cells in oral squamous cell carcinoma.

Swetha Gudiseva, Arvind Babu Rajendra Santosh, Raviteja Chitturi, Vamsikrishna Anumula, Chandrashekar Poosarla, Venkat Ramana Reddy Baddam

Abstract readReview
In one paragraph

Review in Contemporary oncology (Poznan, Poland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Mastocytosis and Skin Cancer: The Current State of Knowledge.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Emerging insights into the biology of metastasis: A review article.Iranian journal of basic medical sciences · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Swetha GudisevaDepartment of Oral Pathology and Microbiology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India.
Arvind Babu Rajendra SantoshDentistry Programme, Faculty of Medical Sciences, The University of the West Indies, Mona campus, Kingston, Jamaica, West Indies.
Raviteja ChitturiSchool of Dentistry, University of the West Indies, St. Augustine, Trinidad and Tobago, West Indies.
Vamsikrishna AnumulaDepartment of Pedodontics and Preventive dentistry, Krishna devaraya Institute of Dental Sciences, Bangalore, Karnataka, India.
Chandrashekar PoosarlaDepartment of Oral Pathology and Microbiology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India.
Venkat Ramana Reddy BaddamDepartment of Oral Pathology and Microbiology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mast cells are initial effective lineage in both humoral and adaptive immunity. They are ubiquitous in skin, mucosa, and in function. They contain biologically essential and dynamic mediators in healthy and harmful conditions of tissue. Mast cell malfunctioning could be attributed to various chronic allergic diseases. Considerately, emerging evidence of mast cell involvement in various cancers shows them to have both positive and negative roles in tumour growth. It mostly indulges in tumour progression and metastasis via angiogenesis, extracellular matrix degradation, and mitogenic activity in the tumour microenvironment. The current paper reviewed research papers on mast cells in oral squamous cell carcinoma through the PubMed database from 1980 to the present date. The present paper is an attempt to summarise the research reports on the role of mast cells in oral squamous cell carcinoma. Further to this note, this paper also outlines the role of mast cells in normal physiological processes and tumour biology.

Indexed as

angiogenesischymasehistaminemast cellsmediatorsoral squamous cell carcinomatryptase

Identifiers

PMID28435394
PMCPMC5385471

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.