Evidence map›Paper›PMID 28435327›Full record

ArticleInternational journal of women's health2017

Effect of menopause on hormonal receptors in ampullae of the fallopian tube with a special reference to the p53 signature.

Rie Urabe, Toru Hachisuga, Taeko Ueda, Toshinori Kawagoe, Tomoko Kurita, Seiji Kagami, Masanori Hisaoka, Yoshihisa Fujino

Open access · goldAbstract read
In one paragraph

Article in International journal of women's health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Natural history of ovarian high-grade serous carcinoma from time effects of ovulation inhibition and progesterone clearance of p53-defective lesions.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rie UrabeDepartment of Obstetrics and Gynecology.
Toru HachisugaDepartment of Obstetrics and Gynecology.
Taeko UedaDepartment of Obstetrics and Gynecology.
Toshinori KawagoeDepartment of Obstetrics and Gynecology.
Tomoko KuritaDepartment of Obstetrics and Gynecology.
Seiji KagamiDepartment of Obstetrics and Gynecology.
Masanori HisaokaDepartment of Pathology and Oncology.
Yoshihisa FujinoDepartment of Preventive Medicine and Community Health, School of Medicine, University of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu, Japan.
University of Occupational and Environmental Health Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAge-related changes in the expression of hormonal receptors have not been well examined in the fallopian tube (FT). We herein report the effect of menopause on the hormone receptors in ampullae of the FTs (AFTs), in comparison with cortical inclusion cysts (CICs) of the ovary.

methodsA total of 84 AFTs and 16 fimbriae of FTs, which were obtained from 26 premenopausal and 58 postmenopausal women; and 27 postmenopausal CICs were immunohistochemically studied for the expression of p53, Ki-67, estrogen receptor-alpha (ER-α), and progesterone receptor A (PRA). Apoptotic cells were identified using a TUNEL assay.

resultsPostmenopausal AFTs showed a significantly lower labeling index (LI) for Ki-67 (

conclusionThe expression of PRA was significantly lower in postmenopausal AFTs than in premenopausal AFTs, whereas the expression of PRA was well preserved in postmenopausal CICs.

Indexed as

apoptosisestrogen receptorfallopian tubep53 signatureprogesterone receptor

Identifiers

PMID28435327
PMCPMC5386599
OpenAlexW2604571883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.