Evidence map›Paper›PMID 28435307›Full record

ArticlePharmacogenomics and personalized medicine2017

Comparison of

Dmitrij Alekseevitch Sychev, Grigorij Nikolaevich Shuev, Salavat Shejhovich Suleymanov, Kristina Anatol'evna Ryzhikova, Karin Badavievich Mirzaev, Elena Anatol'evna Grishina, Natalia Evgenievna Snalina, Zhannet Alimovna Sozaeva, Anton Mikhailovich Grabuzdov, Irina Andreevna Matsneva

Open access · goldAbstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Dmitrij Alekseevitch SychevDepartment of Internal Medicine and Clinical Pharmacology, Russian Medical Academy of Continuing Professional Education, Ministry of Healthcare, Moscow.
Grigorij Nikolaevich ShuevDepartment of Internal Medicine and Clinical Pharmacology, Russian Medical Academy of Continuing Professional Education, Ministry of Healthcare, Moscow.
Salavat Shejhovich SuleymanovSaiko Russian-Japanese Medical Center, Khabarovsk.
Kristina Anatol'evna RyzhikovaResearch Centre, Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare.
Karin Badavievich MirzaevResearch Centre, Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare.
Elena Anatol'evna GrishinaResearch Centre, Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare.
Natalia Evgenievna SnalinaResearch Centre, Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare.
Zhannet Alimovna SozaevaResearch Centre, Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare.
Anton Mikhailovich GrabuzdovDepartment of General Medicine, Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Irina Andreevna MatsnevaDepartment of General Medicine, Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Russian Medical Academy of Continuous Professional Education · RUSechenov University · RUKhabarovsk Scientific Research Institute of Epidemiology and Microbiology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe efficiency and safety of drug therapy depends on the peculiarities of functioning of the P450 cytochrome group and transporting proteins. There are significant differences for single-nucleotide polymorphism (SNP) frequency. MATERIALS AND

methodsWe studied the peculiarities of P450 cytochrome polymorphisms, SLCO1B1 transporting protein, and P-glycoprotein carriage in healthy volunteers in the Nanai ethnic group living in Russia, and compared them to the carriage of SNPs in the Russian population according to literature data.

resultsAfter performing the real-time polymerase chain reactions on the samples from 70 healthy volunteers from the Nanai group, for the

conclusionIn the Nanai population, there are polymorphisms connected with the decrease in safety and efficiency of drug therapy. Studying the ethnic differences might influence the determination of priority in the introduction of pharmacogenetic tests in clinical practice in different regions of Russia.

Indexed as

Asiansethnic groupethnicityEuropeansP450 cytochromeP-glycoproteinpharmacogeneticsSNP

Identifiers

PMID28435307
PMCPMC5386602
OpenAlexW2599097222

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.